B a c kg ro u nd: R e ge ner at io n o f p er io d o nt i u m u si n g a u to lo go u s ma te ria l s ha v e b ee n at te mp ted a s it ad d r es se s sa f et y i s s ue s a nd e n s ur es ea s y ava il ab i li t y. Amo n g t he a u to lo go u s o p tio n s av ai lab l e, us e o f p lat el e t co n ce n tr a te s are p ro mi si n g d ue to e as e o f p ro c ure me nt , h a nd l i n g a nd lo w co s t. P la te let -r ic h p la s ma ( P RP ) i s a n a u to l o go u s p ro d uc t t ha t i s d e ri ved fro m wh o l e b lo o d th ro u g h t h e p r o ce ss o f gr ad i e nt d e n si t y c e ntr i fu ga tio n . W e hereb y re p o rt a ca se o f c hro nic p erio d o nt it i s wi t h i ntr a b o n y d e fec t s i n r ela tio n 4 6 a nd 4 7 tr eat ed wi th P RP co mb i ned wi t h b o ne gra fts wi t h a si x mo n t h fo llo w up . M eth o do lo g y : 5 ml o f p a ti e n t 's ve no u s b lo o d wa s co ll ect ed a nd P RP o b tai ned a fter ce nt r i fu ga tio n . T he p la te let co nce n tra te o b ta i ned wa s us ed i n co mb i na tio n wi t h b o n e gr a f t i n i n tr a b o n y d e fec t i n rel at io n to 4 6 a nd 4 7 . Re s ult s: A r ed uct io n in t h e P ro b i n g p o c ket d ep t h ( P P D) fro m 7 m m (P r e -o p era ti v e) to 3 m m a nd C AL (c li n ica l att ac h me n t le ve l) fr o m 9 m m ( P r e -o p er at i ve) to 5 m m at 6 mo nt h reca ll wa s o b ser v ed r esp ect i ve l y. Co n cl us io n: Si g n i fi ca nt i mp ro v e me n t i n c li n ica l p ar a me ter s s uc h a s P P D, C AL ind ic ate s s uc ce s s o f r e g en er a ti ve t her ap y u si n g P RP wi t h b o ne gra fts .
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.