The recent increased use of steriods, immunosuppressive agents and cytotoxic drugs has been associated with a rise in the incidence of significant fungal disease. The first case of bilateral renal aspergillosis without disseminated involvement is reported. A multitherapeutic approach, including surgical evacuation of masses of hyphae, parenteral antimycotic chemotherapy and topical instillations of amphotericin B, were necessary to clear the kidneys. Newer systemic agents such as 5-fluorocytosine and rifampicin were also used. Treatment of fungal infections of the urinary tract is discussed.
Classically, multicystic kidneys have been described as having no functioning renal parenchyma that, consequently, should not be seen on excretory urography. However, during the last several years, sufficient concentration of contrast medium permitted radiographic visualization of renal tissue in 4 cases of pathologically typical multicystic kidneys.
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