Malnutrition in oral cancer patients leads to poor response to treatment and reduced quality of life. The present study assessed the nutritional status of patients treated for oral squamous cell carcinoma and evaluated the need for implementation of any institutional protocol regarding the type of nutritional intervention employed for these patients. Patients with oral squamous cell carcinoma who had undergone primary tumor resection with or without neck dissection and reconstruction from June 2015 to June 2018 were evaluated. Of the patients with complete data recalled for review, only 25 reported to our Institute, including 12 who had undergone surgery alone and 13 who had undergone surgery plus adjuvant radio and/or chemotherapy. Their nutritional status was assessed by measuring their Mini Nutritional Assessment (MNA) scores, and MNA scores in the groups that underwent surgery alone and surgery plus adjuvant therapy compared by independent sample ‘t’ tests. Of the 12 patients who underwent surgery alone, eight had normal nutritional status, and four were at risk of malnutrition. Of the 13 patients who underwent surgery plus adjuvant therapy, only one had normal nutritional status, whereas 12 were at risk of malnutrition or malnourished. Mean MNA score was significantly higher in patients who had undergone surgery alone than in patients who had undergone surgery plus adjuvant therapy (p=.001). Risk of malnutrition was higher in patients who underwent surgery plus adjuvant therapy than in patients who underwent surgery alone. Postoperative care of patients with oral squamous cell carcinoma should include nutritional management to improve patient prognosis and quality of life.
Purpose
The aim of this review was to systematically analyze the available literature on the correlation between the gray values (GVs) of cone-beam computed tomography (CBCT) and the Hounsfield units (HUs) of computed tomography (CT) for assessing bone mineral density.
Materials and Methods
A literature search was carried out in PubMed, Cochrane Library, Google Scholar, Scopus, and LILACS for studies published through September 2021.
In vitro
,
in vivo
, and animal studies that analyzed the correlations GVs of CBCT and HUs of CT were included in this review. The review was prepared according to the PRISMA checklist for systematic reviews, and the risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies tool. A quantitative analysis was performed using a fixed-effects model.
Results
The literature search identified a total of 5,955 studies, of which 14 studies were included for the qualitative analysis and 2 studies for the quantitative analysis. A positive correlation was observed between the GVs of CBCT and HUs of CT. Out of the 14 studies, 100% had low risks of bias for the domains of patient selection, index test, and reference standards, while 95% of studies had a low risk of bias for the domain of flow and timing. The fixed-effects meta-analysis performed for Pearson correlation coefficients between CBCT and CT showed a moderate positive correlation (r=0.669; 95% CI, 0.388 to 0.836;
P
<0.05).
Conclusion
The available evidence showed a positive correlation between the GVs of CBCT and HUs of CT.
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