Background: Breast lump is one of the commonest complaints with which patients present in breast clinics. As in most cases breast lump ultimately leads to a diagnosis of breast cancer, it is important for women with a breast lump to receive appropriate evaluation. So initial diagnostic approach such as utilization of rapid, inexpensive, presumptive and safe method is utmost important as such methods not only would benefit both patients and clinicians by prompting proper preoperative diagnosis and management but also further limits unnecessary testing and procedures. Aim and objectives of this study was to analyse the diagnostic accuracy of mammogram according to Breast Imaging Reporting and Data System (BI-RADS) score and fine-needle aspiration cytology (FNAC) in patients presented with benign and malignant breast lumps in authors centre.Methods: During this retrospective study from January 2018 to December 2018, the subjects concerned included all the female patients, who were referred to the department of pathology for FNAC of their breast mass and had radiological reports (mammography) with BI-RADS score according to the latest guidelines. The sensitivity, specificity, accuracy, positive and negative predictive values of BI-RADS scores and FNAC in diagnosis of breast diseases was done on the basis of final diagnosis.Results: In this study, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy was 88.57%, 82.46%,75.61%,92.16% and 84.78%, respectively for Mammography (BIRADS) score and 100% for all the parameters on FNAC.Conclusions: According to authors above study findings concluded that FNAC could be considered an ideal initial diagnostic modality in all breast lumps recognized by means of imaging techniques. It is not only considered as safe, cost effective, rapid and presumptive diagnostic method but also further limits unnecessary testing and procedures.

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Uterine sarcoma is a rare verity of smooth muscle tumor, accounting for 2 to 6% of uterine malignancies. Leiomyosarcoma (LMS) represents ~1% of overall uterine tumors and ~25 to 36% of uterine sarcomas. Here we present a case of uterine LMS in a 34-year-old nulliparous woman presented with huge distension of abdomen which was confused to be an ovarian malignancy. She underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy. The diagnosis of LMS is made by histopathological examination after surgery. Surgery is the only treatment and role of adjuvant therapy has not been clearly defined.

Background: Evaluation of colorectal biopsy specimens in non-neoplastic lesions is to identify a pattern of injury that can render a specific diagnosis. It is significant in correlating clinically diagnosed cases and also imparts histological diagnosis in cases with normal colonoscopic appearance having altered bowel habit. The objective of this research is to study the various spectrum of histological findings of colonoscopic biopsies received in a tertiary care centre. Materials and methods: This were a prospective study which included the colonoscopic biopsies from 132 patients received in the department of Pathology, SCB Medical College, Cuttack from January 2020 to December 2021, over a period of 2 years. Results: There were 132 biopsies studied, of which 33.3% showed non-specific colitis, 23.5% Inflammatory Bowel Disease (IBD), 15.2% polyps ,14.4% acute colitis, 5.3% microscopic colitis, 3% eosinophilic colitis, 1.5% granulomatous, 3 cases of Solitary Rectal Ulcer Syndrome (SRUS) and a single case each of amoebic colitis and Melanosis Coli. Conclusion: Histomorphological examination in non-neoplastic colonoscopic biopsies is a diagnostic challenge and an essential arm of multidisciplinary approach to render specific diagnosis and to improve quality of management.