The concept of metabolite profiling has been around for several decades, but only recent technical innovations have allowed metabolite profiling to be carried out on a large scale - with respect to both the number of metabolites measured and the number of experiments carried out. As a result, the power of metabolite profiling as a technology platform for diagnostics, and the research areas of gene-function analysis and systems biology, is now beginning to be fully realized.
Republication of this report is permitted without the need for formal IUPAC permission on condition that an acknowledgement, with full reference together with IUPAC copyright symbol (0 I995 IUPAC), is printed.Publication of a translation into another language is subject to the additional condition of prior approval from the relevant IUPAC National Adhering Organization. This repon gives basic technical information on immunoassays such as test formats and detection systems. Parameters critical for the reliability of this methodology such as matrix interference and cross reactivity are discussed. Guidelines are proposed for precision requirements, standardised evaluation procedures and the distribution of immunoanalytical methods for agrochemicals. Follow-up activities ax^ summarised with the intention of generating a wide data base on the precision and applicability of immunoassays for agrochemical analysis.
1989-1 993).
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