255metallic gold was bound by the alpha globulins. Although radiogold salts have been shown(3 j to interact with the albumin fraction of plasma, Aurcoloid is relatively free of ionic gold.The effect of gelatin in prolonging the retention of Aurmloid #in the circulation was apparently not mediated at the cellular level since colloidal gold was rapidly ingested by the RES regardless of whether the gold particles were coated with gelatin or plasma proteins (4). As Aurcdoid was eventually removed from the circulation by the RES, either the gold-gelatin-alpha globulin interaction was reversible or the total complex was phagocytised. Dissociation of the complex was not demonstrated in plasma electrophoretic patterns of animals injected with gelatin and Aurcoloid.Summary. The relative mobilities of Aurcoloid and gelatin have been demonstrated in vivo and in vitro by paper electrophoretic methods. Addition of Aurcoloid and gelatin to plasma resulted in a radiogold-gelatin complex which migrated at the same rate as alpha globulins. Aurcoloid in plasma did not migrate. The formation of an Aurcoloidgelatin complex was associated with a decreased rate of disappearance of radiogold from the circulation.1. Murray, I. M., and Katz, M.,
Lack of reactivity of IgG autoantibodies with Rhnull red blood cells does not necessarily imply specificity directed towards the Rh system. Recent reports have indicated that occasionally the autoantibodies of warm antibody type hemolytic anemia may have U‐specificity. This report describes an example of auto‐anti‐U occurring in a patient with myasthenia gravis who had no evidence of hemolysis.
It has been emphasized that the maximum reduction in dental caries is obtained with rats fed diets containing 1 per cent phosphorus. Less favorable results have been obtained when the animals received diets with lower concentrations of phosphorus. If a proportionate phosphorus intake is required bv the human in order to obtain the desired results in caries reduction, one can calculate that the adult would then have to ingest approximately 20 gm. of phosphorus per day. This quantity of phosphorus would certainly be objectionable from the dietary and physiologic standpoints. Therefore, it is to be hoped that the human will not require as high a phosphorus concentration in his diet as is needed by the rat in order to obtain the optimal effect in dental caries reduction. Doubling the usual phosphorus content of the human dietary would probably be acceptable from all standpoints.
Five diets were tested for their capacity to promote weight gains in newly-weaned, 19-d-old, rotavirus-exposed pigs. The diets were tested under conditions designed to minimize the stress of weaning. That is, rotavirus-exposed pigs were moved at weaning to an isolation unit, caged individually and fed hourly liquid diets that were high (approximately 26%) and low in protein (approximately 11%). In all experiments, pigs experienced postweaning rotavirus-associated diarrhea and depression in rate of gain. Pigs grew faster: when fed diets high in protein (approximately 26% protein) vs low in protein (approximately 11% protein) and when fed diets containing cows' milk proteins vs proteins from soybean flour. A diet containing antibodies to rotavirus did not ameliorate the weanling diarrhea.
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