Introduction
Obesity has increased worldwide and concerns comorbidity in patients with schizophrenia, and is linked to a high mortality rate in this group. Although bariatric surgery is the gold standard treatment for refractory obesity, it rarely is indicated for subjects with schizophrenia due to psychotic symptoms recurrence.
Objectives
Report weight-loss outcome and psychopathology changes over 36 months follow-up of 5 patients with schizophrenia submitted to bariatric surgery.
Methods
Patients have been followed for 36 months. Clinical and anthropometric assessments such as percentage of excess weight loss (EWL) and body mass index (BMI) have been performed at 6, 12, 24, and 36 months follow-up. The Positive and Negative Syndrome Scale (PANSS) was used to assess psychopathology status. Wilcoxon test was used to assess statistical differences.
Results
The sample included four female and one male subject, with BMI at baseline 42,81± 5,66. The results of BMI and EWL over time are described in Table 1. A significant statistical difference was found between BMI at baseline and at T6, T12, T24, and T36 (p<0,05). EWL was higher at T12 ( compared with T6), but not different from other measurements. PANSS scores at the baseline were 7,7 ± 1,6 for a positive domain, 8,7 ± 2,3 for a negative domain, and 19,2 ± 6 for general psychopathology, with no statistically significant differences during the follow-up.
Conclusions
Despite the small sample, bariatric surgery has been shown a safe and efficient refractory obesity treatment in patients with schizophrenia.
Disclosure
No significant relationships.
Resumo: O estudo tem o propósito de verificar as contribuições da aplicação da ferramenta Produção Mais Limpa em uma fábrica de cadernos localizada na cidade de Campina Grande -PB. Para tanto, executou-se uma pesquisa descritiva de caráter exploratório. Quanto aos meios configura-se como qualitativa, conduzida sob a forma de estudo de caso. Os dados primários foram obtidos por intermédio de uma entrevista estruturada com o gerente de produção da fábrica. Para tanto, o roteiro está segmentado do seguinte modo: A empresa, descrevendo o objeto de
The use of prestressed precast hollow core slabs has intensified as technological advances. However, the knowledge of the structural behavior when openings are inserted into this element is still limited, mainly due to the shear force. Therefore, the present study aims to analyze the structural behavior of the shear test of prestressed hollow core slabs with openings. In this paper, three types of hollow core slabs were tested: no openings, a central opening and side openings; using experimental and numerical methodology. The experimental test was carried out in the Federal University of São Carlos, and the numerical analysis used the software ABAQUS. All results were compared with three standard formulations (i.e., NBR, ACI and Eurocode), in order to verify its accuracy. In the end, the numerical results demonstrated that the developed model (CDP) presented results close to the experimental results. For the hollow core slab with a central opening, a rupture occurred in the web adjacent to the opening. On the other hand, for the hollow core slab with side openings, the rupture occurred at the edge of the web. Therefore, it was possible to conclude that the openings influence the main web tensions, being responsible for the diagonal model stress rupture. Finally, the Brazilian and Eurocode standard formulations proved to be good estimators of the resistant shear force.
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