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Postoperative radiotherapy was applied to 106 cases of malignant glioma who referred to our department between January 1990 and December 1993. Forty-one of the patients were fem ale and 65 w ere mal e. M ean age w as 45.8. Histologically 57 of the cas es w ere anap lastic astrocytoma (AA) and 49 were glioblastoma multiforme (GM). Forty-three cases were resected subtotally, 60 were resected totally and only biopsy was done in 3 cases. Postoperative radiotherapy was given as daily fractions of 1.8 Gy. Following 45 Gy to the whole brain the treatment fields were shrinked and the doses were 41.5% and 16.5% respectively for the whole group, 57.8% and 28.0% for AA, 22.4% and 2.4% for GM. When prognostic factors that would effect the d uration of survival were evaluated with univariant analysis, it was found that histologic type (p<0.0001) and age (p==0.018) effected survival while sex (p:::0.638) and operation type (p==0.425) had no significant effect. Multivariant analysis showed that histologic type (p<0.0001) anda age (p:::0.052) were independent prognostic factors.

47 consecutive lung cancer cases were trenaed with postoperaHve radiotherapy. The operation types were tumoredomy in 2(4.3%), segmentectomy in 2 (4.3%), lobectomy in 34 (72.3%), pneumonedomy in 9 (19.1 %) of cases. Dis~ tribution of pal:hological stages were as follows; 3 patients (6.4%) stage II, 21 patients (44.7%) stage IIIA, 23 paHents (48.9) stage IIIB. Postoperative radiotherapy indications were macro~ scopic residual disease for 17 cases (36.2%), microscopk :residual disease foır 15 cases (31.9%) and nodal involvement for 27 cases (57.4%). All cases received 50 Gy {2 Gy/day) from ante~ rior-posterior Helds, induding primary tumOY and mediastinum while 17 of them pı:esenting residual mac:roscopic tumor additional 5x2Gy. Chemotherapy was given before :radiotherapy in 5 patients (10.6%), and after radiotherapy in 13 patients (27.7%). Median follow up was 43 months (13~71 months). During this period local recurırence rate was 31.8%, regional re~ currence rate was 23.4% and distant mestastasis r<ııte was 38.3%. Median overall survival was 14 months (9% CI 12-16 months). Overall sunrival ırates for 11 3, and 5 years weı:e 69.6% 17.1% and 10.2%, respedively. 5 years su:rvival in !ltage HIA and Hib cases wHh are 15.3% ad 6.4% :respedively. These results suggesi: that the role of postoperative radiothe:rapy should be tested in larger and controUed pırospective studies.