Short-term treatment with bFGF enhanced collateral development without increasing neointimal accumulation at sites of vascular injury. Although VEGF did not increase collateral development as administered in this study, it significantly exacerbated neointimal accumulation. These data provide support for the clinical investigation of bFGF in selected patients with ischemic heart disease.

Summary:Intracardiac masses are often diagnosed by transthoracic echocardiography (WE). Transesophageal echocardiography (TEE) improves overall visualization of masses, especially those located in the posterior cardiac structures. Masses in the heart are most commonly due to thrombi or valvular vegetations; however, a variety of tumors may also present as cardiac masses on echocardiography. Tumors of the heart most commonly occur in the setting of metastatic disease, usually from malignancies of the breast, lung, or from malignant melanoma. Primary cardiac tumors occur much less frequently and are usually benign. Atrial myxomas constitute nearly one-half of reported primary cardiac tumors. The following discussion details the findings of five cases that illustrate the spectrum of intracardiac tumors detected by echocardiography and reviews the relevant literature. rior cardiac structure^.^ Masses in the heart are most commonly due to thrombi in the presence of left ventricular systolic dysfunction or atrial fibrillation, or to valvular vegetations in the setting of endocarditis. Less commonly, a variety of intracardiac tumors may be detected by echocardiography. Tumors of the heart most commonly OCCUT in the setting of metastatic disease, usually from malignancies of the breast, lung, or from malignant melanoma. About 20% of patients with malignancies reportedly have cardiac involvement? In contrast, primary cardiac tumors occur much less frequently and are usually benign. Atrial myxomas constitute nearly one-half of reported primary cardiac tumors? The following discussion details the findings of five cases of intracardiac masses, diagnosed initially by echocardiography, and reviews the relevant literature. Case Presentations

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In this large cohort of women, exercise echocardiography provided key prognostic information incremental to clinical and exercise testing data.