A 10-year-old female patient presented with a 3-week history of intermittent, colicky abdominal pain, weight loss, and bloody diarrhea. Laboratory investigations were significant for normocytic anemia. Colonoscopy performed to rule out inflammatory bowel disease revealed a large polyploid mass obstructing the lumen of the ascending colon (Fig. 1). Computed tomography scan of the abdomen showed intussusception of the ascending colon with the mass as a lead point (Fig. 2). The patient underwent a laparotomy and a 5 cm  5 cm  3 cm polypoid mass in the mid ascending colon was seen and resected (Fig. 3). Histopathological examination of the mass revealed spindle cell proliferation, focal necrosis, ulceration, and granulation tissue (Fig. 4). Immunohistochemistry staining was negative for desmin, S100, synaptophysin, chromogranin, CD34, and anaplastic lymphoma kinase (ALK). The patient was diagnosed as having inflammatory myofibroblastic tumor (IMT) and was discharged home with instructions on close follow-up.IMT is a rare tumor with a tendency toward local recurrence, infiltrative growth, vascular invasion, and possible malignant sarcomatous transformation (1). The lung is the most common presenting site, followed by the omentum and mesentery (1). Intestinal presentations with intussusception are rare (2). The etiology of IMT remains obscure, with the neoplastic or inflammatory nature debatable (1,3). Histopathologically, IMT is characterized by spindle-shaped cells with chronic inflammatory cell infiltrates (1,3). The tumor cells diffusely express vimentin, ALK, CD68, desmin, smooth muscle actin, p53, S100, CD34, and CD117 (1,2,4). Immunostaining is positive for ALK in 34% to 56 % of patients with IMT (2,4). IMT may recur in 15% to 37% of patients (1,4). Complete surgical resection with close follow-up is indicated (4). Intraabdominal IMT may present with intussusception; hence, detailed history, physical examination, and imaging studies are necessary for early recognition and diagnosis.