Pseudoangiomatous stromal hyperplasia (PASH) of the breast is a benign condition generally seen as an incidental finding of biopsies for other causes. In some rare cases, it can evolve with expressive growth of breast tissue, leading to large breasts. The present study presents a case report of a patient who started with breast hypertrophy during lactation, evolving with gigantomastia, and arrived at the office 3 years after gestation with breasts of 6.2 and 4.3 kg and growth of accessory breast and axillary lymph nodes. The patient was emaciated, with bodily pain and psychological distress. Computed tomography was performed with the finding of diffuse retroglandular nodules and axillary and mediastinal lymph node enlargement, without being able to rule out the lymphoproliferative process. Then, core biopsies were made in several places on the breast whose pathological examination revealed PASH samples. Bilateral mastectomy was performed as a surgical treatment, with resection of the left accessory breast and left axillary lymph node, and breast reconstruction, with placement of silicone prostheses and graft of the areola-papillary complex, together with a plastic surgeon. She evolved in the postoperative period with good healing of the surgical wound, weight gain, necrosis of the areola-papillary complex and with severe psychiatric disorder, which was treated appropriately by psychiatrists, with remission of symptoms. This case report presents a rare evolution of PASH with gigantomastia, bringing intense physical and psychological distress to the patient, whose treatment chosen was total surgical resection of the breast tissue and aesthetic reconstruction.
Sepsis is a potentially fatal clinical syndrome characterized by an abnormal response to infection associated with organic dysfunction. It is a relevant cause of admission to intensive care units (ICUs) and related to increased morbidity and mortality rates. This study aimed to evaluate the epidemiological profile of adult ICU patients of Lauro Wanderley University Hospital (HULW) in the municipality of João Pessoa (PB) to determine the risk factors associated with increased mortality in patients with sepsis. This retrospective and observational methodological study evaluated the epidemiological profile and characteristics of patients with sepsis, aiming to analyze the risk factors related to increased mortality. The mortality risk analysis was performed in two parts. The first was made from Pearson's chi-square test to determine the association between categorical
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