Non-surgical mechanical treatment associated with the use of amoxicillin and metronidazole led to an improvement in all clinical parameters studied, except for CAL, and significantly reduced the amount of subgingival Tf and Td.
The aim of this study was to evaluate the occurrence of Porphyromonas gingivalis in patients with periodontitis in Brazil and investigate whether there is a relationship between your occurrence and gender and age. Analysis was performed of 1,386 results of microbiological examinations of samples of subgingival microbiota in patients with periodontitis. Collection was performed by periodontists in private practice and processed by culture in clinical laboratory of oral microbiology. The chi-square test was used to verify the association of occurrence of P. gingivalis with gender and age. It was observed that 59% of examinations were of female patients and 41% were of male patients, most of which aged more than 40 years (64.3%). The occurrence of P. gingivalis was 17.8%. There was no significant difference in the presence of this bacterium in the different age ranges, yet there was a significantly higher occurrence in males. It was observed that, regardless of the age range, the occurrence of P. gingivalis was always significantly higher in males. It was concluded that the occurrence of P. gingivalis in patients with periodontitis in Brazil was 17.8% and was associated with gender, yet had no association with the age range.
Objetivo: avaliar as alterações clínicas e microbiológicas resultantes do tratamento periodontal não-cirúrgico associado ao uso de amoxicilina e de metronidazol, em indivíduos portadores de periodontite agressiva (PA), pela qPCR. Material e métodos: 15 indivíduos com PA receberam tratamento periodontal não-cirúrgico e, 45 dias após o término do tratamento, foram medicados com os antimicrobianos. Dados clínicos e amostras de biofilme subgengival foram coletados no dia do exame inicial, 45 dias após o término do tratamento periodontal não-cirúrgico e 1 mês após o uso dos antimicrobianos. Após 3 e 6 meses, apenas novos dados clínicos foram coletados. A presença e a quantificação das bactérias Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythensis, Treponema denticola e Dialister pneumosintes foram determinadas através da PCR em tempo real. Resultados: Todos os parâmetros clínicos, com exceção do nível clínico de inserção, melhoraram significativamente (p < 0,05) no 3 o. mês após a terapia não-cirúrgica associada com antibióticos. Houve redução significante (p < 0,05) nas quantidades de T.d. e T.f.. Após 1 mês, houve reduções significativas (p < 0,05) nas freqüências de P.g. e de T.f.. Conclusões: O tratamento mecânico não-cirúrgico, associado ao uso de amoxicilina e metronidazol, levou à melhora de todos os parâmetros clínicos estudados, exceto do nível clínico de inserção, e reduziu significativamente as quantidades subgengivais de T.f. e T.d.. Palavras-chave: Periodontite agressiva. Reação em cadeia da polimerase. Microbiologia. Agentes antimicrobianos. Amoxicilina. Metronidazol.
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