Results: Administration 40 mg/day of atorvastatin significantly reduced the mean RASS score and increased delirium-free days at both morning and afternoon time points compared to the control group (p < 0.05). Conclusions: Administration of atorvastatin had a significant positive effect on delirium status in patients admitted to the ICU.

Tea grows in the contaminated soils, absorbs the heavy metals, and enters them into the human food chain. The concentrations of Pb, Cd, Cu, As, and Hg of the imported black tea leaves to Hormozgan Province were evaluated by atomic absorption spectrometer. Then, the Hazard Quotient (HQ) and Hazard Index (HI) levels of heavy metal intakes were calculated to estimate the health hazard for consumers. The Pb, Cd, Cu, As, and Hg concentrations in the Sri Lankan and Indian blank tea were 0.14, 0.017, 11.29, 0.057, 0.0076 mg/kg, and 0.21, 0.02, 14.56, 0.067, 0.01 mg/kg, respectively. It was found that except for As concentration in Indian black tea were higher than Sri Lankan black tea. The HQ and HI levels of all studied metals were less than one, but they were higher in Indian black tea compared with the Sri Lankan black tea. The HI of Indian and Sri Lankan black tea samples were 0.061 and 0.048, respectively, which indicated no significant health hazard for tea consumers. The results showed that the consumption of the studied tea could not have any risk of heavy metal exposure.

A one-pot pseudo four-component reaction between a variety of 2-hydroxy-1,2-diarylethanone derivatives and ammonium acetate or amines has been developed to synthesize substituted pyrazines under catalyst-free and solvent-free conditions. This procedure provides a synthetic method to access pyrazine derivatives in excellent yields under green conditions.

Nano-eggshell/Ti(IV) as a novel naturally based catalyst was prepared, characterized and applied for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives. The characterization of nano-eggshell/Ti(IV) was performed using Fourier Transform Infrared spectroscopy, X-ray Diffraction, Field Emission Scanning Electron Microscopy, Energy-Dispersive X-ray Spectroscopy, and Thermo Gravimetric Analysis. Dihydropyrano[2,3-c]pyrazoles were synthesized in the presence of nano-eggshell/Ti(IV) via a four component reaction of aldehydes, ethyl acetoacetate, malononitrile and hydrazine hydrate at room temperature under solvent free conditions. The principal affairs of this procedure are mild condition, short reaction times, easy work-up, high yields, reusability of the catalyst and the absence of toxic organic solvents.

In the new era, many people seek their health-related information through the Internet due to the increasing access to this technology. Searching online health information can affect the health behavior. This study aimed to investigate the correlation between online health information-seeking behavior and a healthy lifestyle during pregnancy in a sample of Iranian pregnant women. This cross-sectional study was conducted among pregnant women admitted to health centers of Eghlid city, Fars province, Iran in 2019. A total of 193 women participated in the study. The required data were gathered using two validated questionnaires to measure the online health information-seeking behavior and the healthy lifestyle practices of the participants. The collected data were analyzed through descriptive statistics and Pearson correlation coefficient using SPSS version 22. Online health information experience and its subscales showed no statistical correlation with a healthy lifestyle. Age and education did not correlate with online health information-seeking behavior. Age had a statistical correlation with a healthy lifestyle, but education had the same correlation only with some subscales of a healthy lifestyle. The findings were surprising, suggesting that online health information-seeking behavior does not affect the lifestyle of pregnant women. These finding and probable explanations are discussed, but due to the limited literature on the subject, further studies are recommended to be conducted.