Introduction. Anastomotic leaks are most of the complications after pancreaticoduodenectomy. About 45% followed with fistula formation. The study aimed to discover intraoperative pancreatic assessment associated with postoperative pancreatic fistula (POPF). Method. A cross-sectional design study carried out enrolling patients with tumor of the pancreatic tumors whose underwent pancreaticoduodenectomy. Pancreatic duct diameter, pancreatic texture, the use of stent in the pancreaticojejunal anastomosis, and pancreaticojejunal anastomosis' technique were the independent variables in the study. While the postoperative pancreatic fistula (POPF) referred to a dependent one, these variables analyzed using the Spearman test due to abnormality data distribution. Results. Of 70 subjects enrolled in the study, Subjects with no POPF found in and with POPF noted in 78.6% subjects and those with no POPF in 21.4% subjects. Of the subjects with POPF, type A found in 69.1%, type B in 14.5%, and type C 16.4% subjects, respectively Conclusion: Intraoperative assessment of the pancreatic duct diameter associated significantly in predicting pancreatic fistula after pancreaticoduodenectomy.
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