Megaloblastic anemia is rare in infants and is generally due to vitamin B12 (cobalamin) deficiency in the mother. Neurologic symptoms of vitamin B12 deficiency include irritability, failure to thrive, hypotonia, and developmental regression/delay. Herein we present 2 infants with vitamin B12 that developed movement disorder 5 d after initiation of vitamin B12 treatment. Symptoms included tremor and myoclonus, involving in particular the face, tongue, and hands. Clinical findings in infants associated with vitamin B12 deficiency vary, and temporary involuntary movement can be observed during vitamin B12 therapy. (Turk J Hematol 2011; 28: 317-22) Key words: Involuntary movement, vitamin B12 deficiency, infant Received: June 11, 2010 Accepted: October 19, 2010 Özet Süt çocuklarında megaloblastik anemi nadirdir ve genellikle annelerdeki vitamin B12 eksikliğinin bir sonucudur. Kobalamin eksikliğinin nörolojik semptomları huzursuzluk, büyüme geriliği, hipotoni ve nöro-gelişimsel becerilerde gerileme/gecikmeyi içerir. Bu makalede kobalamin tedavisinin 5. gününde özellikle dil, yüz, elleri içine alan tremor ve miyoklonus gibi istemsiz hareketler gelişen, kobalamin eksikliği olan, iki süt çocuğu sunuldu. Süt çocuklarında kobalamin eksikliği farklı klinik bulgularla karşımıza gelebilir ve tedavisi sırasında geçici istemsiz hareketler görülebilir. (Turk J Hematol 2011; 28: 317-22)
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.