Background: MDRTB is a global health concern with its current prevalence in India being 2.3% and 17.2% respectively among newly diagnosed and previously treated cases. Besides its clinical impact, the disease affects the QOL of patients suffering from MDR-TB. The objective of the study was to assess the quality of life among MDR-TB cases in comparison with non-MDR TB cases and TB cured subjects (Category I, RNTCP).Methods: A cross sectional study was conducted in all the 14 TUs under District Tuberculosis Centre of Municipal Corporation of Bengaluru (BBMP). Study subjects comprised of 52 MDR-TB Cases, 53 Non-MDR-TB cases and 54 Category I TB cured subjects. WHOQOL BREF questionnaire was used to assess the QOL among study subjects. Median [IQR] scores of QOL in each of the domains among various groups were compared using Kruskal Wallis test. P<0.05 was considered as statistically significant.Results: Median age among MDRTB cases was 35 years [IQR: 26-50] whereas it was 37 years [IQR: 28-47] among Non MDRTB cases and 30.5 years [IQR: 22-45] among TB cured subjects. Out of 52 MDRTB cases, 26(50%) were females compared to 14 (26.4%) among Non MDRTB cases and 26(48.1%) among TB cured subjects (p=0.0024). As compared to non MDRTB cases, physical and environmental domains’ scores of MDRTB cases were significantly low (p=0.01 and p=0.001 respectively).Whereas, as compared to TB cured subjects, physical and psychological domains’ scores of MDRTB cases were significantly low (p<0.001 and p<0.001 respectively).Conclusions: The QOL of patients suffering from TB is affected and the impact is even worse in MDRTB. Hence prompt treatment of TB and early diagnosis of MDRTB will reduce the disease severity and improve the QOL.
Background: Delirium is an acute disorder of attention and cognition. It occurs in 20% to 79% of hospitalized older patients. It is also common in ICU patients, occurring in 20% to 50% of non-mechanically ventilated ICU patients and in 60% to 80% of mechanically ventilated ICU patients. Hence delirium is a common, serious, and often fatal condition among older patients. The present study attempts to address the prevalence of Delirium in the Indian elderly population.Methods: A cross sectional study was conducted between January 2019 to June 2019 in a 50 bedded intensive care unit of a tertiary care hospital in Bengaluru, Karnataka. A total of 300 elderly patients aged 60 years and above, satisfying the inclusion criteria was included in the study. Patients were assessed for the presence of delirium within 24 hours of admission using Confusion Assessment Method for Intensive Care Unit (CAM-ICU). Various qualitative variables were expressed in terms of proportions.Results: Prevalence of delirium among elderly, non-ventilated ICU patients was 30% (90 out of 300 patients). Among them, 50 (55.5%) were females and remaining 40 (44.5%) were males. Mean age of the patients was 76 years. About 50 (55.5%) of them belonged to age group of 70-79 years. Most of the delirium patients (44.5%) belonged to hypoactive type of delirium followed by hyperactive (33.3%) and mixed (22.2%) type of delirium.Conclusions: Delirium in elderly ICU patients is significantly prevalent, which is a poor prognostic factor, leading to higher morbidity and mortality. Of the three subtypes- hypoactive delirium is the most common type of delirium among elderly. Yet, it is often overlooked or under-diagnosed. Hence clinicians and/or trained nursing staff managing the patients in the ICUs, should routinely screen the patients for delirium, using brief screening measures, which in turn can improve the patients’ outcome.
: Throughout the globe, vaccines have saved countless lives, improved health and wellbeing. Vaccine hesitancy at the individual and community level risks the public health consequences of vaccine-preventable disease outbreaks.1. To find out the proportion of vaccine hesitancy 2. To determine the factors contributing to vaccine hesitancy for childhood vaccinations in urban slums of Bengaluru Rural District, Karnataka. A community based cross sectional study was carried out in 8 urban slums of Bengaluru Rural District from August 2019 to September 2020. Children aged 0-59 months were primary subjects and mothers / primary caregivers of children 0-59 months were secondary study subjects. Data Collection was done using a predesigned, pretested questionnaire and by reviewing immunization cards. Data analysis was done using SPSS version 20. The association between Vaccine hesitancy and predictor variables was tested by using chi –square test. Vaccine hesitancy was present among 75% of the mothers / primary care givers. Main Reasons for Vaccine hesitancy reported were fear of vaccination side effects, sickness of child, unaware of availability of vaccines, felt unnecessary to get child vaccinated, The present study reported delay in vaccination for the birth dose of BCG (66%), Hepatitis B (40%); OPV (9%). Vaccine hesitancy was found to be more in nuclear families, low socio-economic class, in female children, birth order of 3 or higher, among mothers who had primary education and are homemakers. This difference was found to be statistically significant. Among the characteristics of children, the gender of the child and birth order was found to be significantly associated with vaccine hesitancy. One of the major reasons found in this study for Vaccine hesitancy was concern regarding safety. Therefore vaccination programmes and policies have to feature strong community engagement strategies to increase awareness about the vaccines and remove fears.
India has the largest population of adolescents in the world (1/5th of world’s adolescents)with4-33% prevalence of mental health disorders. The present study was conducted to assess the mental health status of adolescent school going children in Karnataka. A cross sectional study was conducted among 375 adolescent school going children aged 10-15 years in a private school in Karnataka (June-August 2019). Students were interviewed by pretested questionnaire after obtaining informed assent from the school administrators and primary care givers. The questionnaire included 4 different domains viz., Educational, Physical health, Emotional and Social factors. Scores ranged between 0 – 41 and interpreted as higher the scores better the mental health status of student. Data was analyzed using SPSS software version 24.Out of 375 participants, 48.8% were girls and 51.2% were boys with mean age of 12.7 yrs. Overall 12.5% students had abnormal mental health status, which was more among girls (15.4%) compared to boys (9.9%) and it was statistically significant (p < 0.021). Of 4 domains, physical health factor was most affected (17.3%), followed by educational factor (15%). Gender-wise, educational domain was most affected among boys (17.7%, p = 0.034) and physical health domain among girls (20.2%, p<0.001), which was statistically significant.This study shows that abnormal mental health status is prevalent among adolescents and more among girls. Of the 4 domains, Physical health was most affected. This problem needs addressal with well defined school-based intervention programs.
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