Background Following the first investigational study on the use of extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma published in 1983, this technology has received continued use and further recognition for additional earlier as well as refractory forms. After the publication of the first guidelines for this technology in the JEADV in 2014, this technology has maintained additional promise in the treatment of other severe and refractory conditions in a multidisciplinary setting. It has confirmed recognition in well-known documented conditions such as graft-versus-host disease after allogeneic bone marrow transplantation, systemic sclerosis, solid organ transplant rejection including lung, heart and liver and to a lesser extent inflammatory bowel disease.

BackgroundFollowing the first investigational study on the use of extracorporeal photopheresis for the treatment of cutaneous T‐cell lymphoma published in 1983, this technology has received continued use and further recognition for additional earlier as well as refractory forms. After the publication of the first guidelines for this technology in the JEADV in 2014, this technology has maintained additional promise in the treatment of other severe and refractory conditions in a multidisciplinary setting. It has confirmed recognition in well‐known documented conditions such as graft‐vs.‐host disease after allogeneic bone marrow transplantation, systemic sclerosis, solid organ transplant rejection including lung, heart and liver and to a lesser extent inflammatory bowel disease.Materials and methodsIn order to further provide recognized expert practical guidelines for the use of this technology for all indications, the European Dermatology Forum (EDF) again proceeded to address these questions in the hands of the recognized experts within and outside the field of dermatology. This was done using the recognized and approved guidelines of EDF for this task. All authors had the opportunity to review each contribution as it was added.Results and conclusionThese updated 2020 guidelines provide at present the most comprehensive available expert recommendations for the use of extracorporeal photopheresis based on the available published literature and expert consensus opinion. The guidelines were divided into two parts: PART I covers Cutaneous T‐cell lymphoma, chronic graft‐vs.‐host disease and acute graft‐vs.‐host disease, while PART II will cover scleroderma, solid organ transplantation, Crohn’s disease, use of ECP in paediatric patients, atopic dermatitis, type 1 diabetes, pemphigus, epidermolysis bullosa acquisita and erosive oral lichen planus.

The harmony of smile is determined not only by the shape, position and colour of the teeth but also by the colour of the gingival tissues. Excessive gingival pigmentation is a major aesthetic concern for many people. Though, it is not a medical problem but many people complain of dark gums as unesthetic. Aesthetic gingival depigmentation can be performed in such patients with excellent results. A case is reported here in which a simple and effective gingival depigmentation was performed with the use of electrosurgery which provides increased satisfaction in patients

Excessive gingival pigmentation is a major esthetic concern for many people. The gingiva is an important intraoral tissue which when affected particularly by pigmentation is mainly responsible for the unpleasant appearance. A harmonious smile accounts for a perfect balance between the pink and white component of oral cavity. It mainly affects the confidence, self-esteem, and esthetics of an individual, which can also have a psychological impact on them. Melanin pigmentation is known to be caused by melanin granules within the gingival epithelium. In this case report, a split-mouth depigmentation was done using electrosurgery and diode laser with melanin hyperpigmentation in the anterior maxilla and mandible which provides increased satisfaction in patients.

Interdisciplinary approach helps the specialists of contributing disciplines immensely in diagnosis, treatment planning, execution of planned treatment and problem solving for any untoward complication. Orthodontic treatment may be adjunctive to periodontal therapy or vice versa. Periodontal problems might lead to occlusal abnormalities which may require orthodontic correction. Of equal importance is that treatment should not induce damage to the periodontal structures. It is imperative that periodontal tissues are healthy before prosthodontic treatment commences, and additional periodontal treatment is commonly indicated to facilitate improved prosthodontic treatment outcomes.