Background:The contemporary lifestyle has made Cancer as one of the most deadly diseases. Treatment modalities of cancer are many, while chemotherapy seems to be the most common. Though, chemotherapy subsides the disease, it has many side effects in which Chemotherapy induced Nausea and Vomiting (CINV) is frequent. This study aims to evaluate various antiemetics in the prevention of Chemotherapy induced Nausea and Vomiting in cancer patients specifically in Breast, Lung, Cervix and Head & Neck cancers so that the rate of emesis, efficacy and comparative efficacy of different antiemetic combinations in cancer patients can be determined. Methods: A prospective observational study was carried out at a tertiary care hospital in Tamilnadu, South India between January to June, 2015 in which 241 cancer patients receiving antiemetics in their prescriptions meeting our inclusion criteria were analyzed using standard guidelines. A well designed data collection form was prepared to collect the datas. Results: It was observed from our study that the efficacy of different combination of antiemetics, mostly given as triple based regimen, relied on the treatment regimen of the particular cancer, thereby its emetogenic level and NCI-CTC grading score and it was found out that Ramosetron based triple antiemetic regimen was slightly better than Granisetron based regimen to control CINV. Conclusion: It is the need of the h to promote optimal antiemetic medication and ensure that cancer patient receives evidence-based, effective treatments for their health problems.
Introduction: Diabetes mellitus is a chronic disease that occurs when the pancreas is no longer able to make insulin, or when the body cannot make good use of the insulin it produces. It can be controlled using oral hypoglycaemic agents and/or insulin and lifestyle modifications. This study examines the role of pictograms in educating the diabetic patients about proper medication use and lifestyle modifications. It is an open label, observational comparative study. Objectives: To educate diabetic patients about proper medication use and lifestyle modifications using pictograms. To identify whether comprehension of pictogram differs based on gender, age group, level of education and compliance to medications in diabetic patients and to develop a leaflet containing pictograms which convey information about lifestyle modifications and medication use in diabetic patients. Method: A prospective-observational comparative study of 6 months duration was undertaken with 100 participants for Phase-1 (Survey; n=100) to select the best understood pictograms from the 24 pictograms selected. This set was carried out for Phase-2 (one-on-one interview; n=100), which had Guessability and Translucency as its components. Guessability study was carried out in 50 diabetic patients and their response to pictograms was recorded in a 3 point Likert scale. Modifications were made to the pictograms based on the difficulties faced by the patients in understanding the pictograms. These modified pictograms were used for Translucency study and result was obtained using 5 point Likert scale. We use student t-test and Chi-Square test using SPSS 19 to analyze the data. Results: The results of this study show that pictograms are generally well understood by the diabetic patients when the intended meaning of the pictograms are explained and are accompanied with text. The statistically significant p values were obtained only with levels of education in both Guessability (0.040) and Translucency (0.050). The overall Guessability (all pictograms included) was 69.6% and the overall Translucency was 90.9%. Conclusion: The result from this study suggests that pictograms play a vital role in educating patients and can be used as an effective counselling aid in a low-literacy group of people. INTRODUCTIONDiabetes mellitus is a chronic disorder that occurs when pancreas is no longer able to make insulin, or when the body cannot make good use of the insulin it produces. Insulin is a hormone made by the pancreas that acts like a key to let glucose from the food we eat pass from the blood stream into the cells in the body to produce energy. All carbohydrate foods are broken down into glucose in the blood. Insulin helps glucose get into the cells. Inability to produce insulin or use it effectively leads to hyperglycaemia. Over the long-term high glucose levels are associated with damage to the body and failure of various organs and tissues. 1 According to recent estimates, approximately 285 million people worldwide (6.6%) had diabetes in 2010 and by ...
Background: Cushing syndrome is a systemic disorder, occurs as a result of abnormal blood level of cortisol. Prolonged use of topical corticosteroid may cause Cushing syndrome which is very rare and only a few patients have been reported to date in the literatures. Objectives: To evaluate the prompt medical care given for topical corticosteroids induced Iatrogenic caushing syndrome. Results: Clinical symptoms are reduced within one week of treatment with Methotrexate, Prednisone and emollients. Conclusion: Results of the study indicates that the health awareness should be created among general public to avoid the unnecessary drug induced complications.
Ewing's sarcoma is a very rare type of malignant tumour that grows in bones or the soft tissue around the bones, such as cartilage or the nerves. It usually affects people from the ages of 10 to 20 and has a high rate of being cured. Children with Ewing's sarcoma that hasn't spread have cure rates as high as 80%. Even if the treatment works, patients still need to follow up for many years. Ewing's sarcoma can return even a decade after the diagnosis. This is a case of 9-year-old male patient with a known case of Ewing's sarcoma diagnosed 3 years back. He was treated according to National Comprehensive Cancer Network recommendations for Ewing's sarcoma and later he defaulted for 1 year. Now he is at the stage of metastasis of Ewing's sarcoma. The study points out that there is an utmost importance of regular follow ups and therapeutic value of completing the treatment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.