The monitoring of health in fish farms partly relies on the availability of exact serum biochemistry reference intervals as these data provides a base for the interpretation of tests to assess health status. Serum biochemistry reference intervals for Clarias gariepinus cultured in earthen pond system was established following evaluations of two hundred and forty healthy fish sampled across eight farms. Other results include Lactate dehydrogenase 28.06-54.03 mg/dl in juveniles and Urea 1.96-4.11 mg/dl in juvenile fish. These data will serve as a tool for the monitoring of health and nutritional condition of Clarias gariepinus farmed in ponds at the Southern Guinea Savanna agro-ecological zone of Nigeria.
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