Context and objectives: West Africa has a very rich ethnozoological heritage due to its rich biodiversity, history and culture. Due to its location in a biodiversity hotspot, its agro-pastoralist traditions and its role during the maritime discoveries of the Renaissance, West Africa has a long list of animals and animal parts that have been used in its folk medicine. These uses can still be found in many historical documents and pharmacopeias. Bridelia ferruginea, Combretum glutinosum and Mitragyna inermis are tropical and subtropical medicinal plants widely used in general traditional African medicine and in West Africa in particularly, including Benin, Nigeria, Burkina Faso and Ivory Coast to treat many diseases such as bladder troubles, diabetes, dysentery, arterial hypertension, rheumatism pain. This study aims to do a literature review of these three tropical plants on their biological and pharmacological properties on veterinary medicine Methodology and Results: A thorough literature search was done and plants little studied Bridelia ferruginea, Mitragyna inermis and Combretum glutinosum were chosen in the search for their anthelmintic activity against gastrointestinal parasitic nematodes of small ruminants in Djallonké. Also to confirm their use in traditional veterinary medicine in West Africa. Conclusion and application of results: This literature review of their extracts properties showed that the plants possessed wide-reaching pharmacological actions, including anti-diabetic, cardiovascular disease antibacterial, anti-inflammatory, antispasmodic and antiplasmodial and justifies their use in traditional medicine for treating various diseases. This manuscript intends to be a starting point to these future investigations.
Les effets anthelminthiques de la poudre de feuilles de Zanthoxylum zanthoxyloïdes et de Newbouldia laevis ont été évalués in vivo sur Haemonchus contortus, Trichostrongylus colubriformis et Oesophagostomum columbianum chez les chevreaux Djallonké âgés de 4 à 5 mois. Les doses de 3,2 et 4,8 g/kg poids vif ont été administrées par voie orale pendant trois jours consécutifs. Le taux de réduction de l'excrétion fécale est respectivement passé, entre une et trois semaines après traitement de 55% à 84% pour Z. zanthoxyloïdes et de 82% à 97% pour N. laevis. Les poudres de Z. zanthoxyloïdes et de N. laevis ont significativement (p < 0,05) réduit l'excrétion des oeufs des strongles sans effet-dose mais avec une efficacité plus marquée pour N. laevis. Au bilan parasitaire, les deux plantes se sont montrées efficaces sur la viabilité des vers adultes de H. contortus sans effet-dose pour Z. zanthoxyloïdes mais dose dépendante pour N. laevis. Elles sont sans effets sur le nombre des vers adultes de T. colubriformis et de O. columbianum. Chez H. contortus, la poudre de Z. zanthoxyloïdes a réduit de façon significative (p < 0,05) et sans effet-dose le nombre d'oeufs par ver femelle (prolificité) contrairement à N. laevis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.