Objective. The aim of this systematic review was to investigate the advances in the study of medicinal plants and their biologic effects on periodontitis in animal models. Study Design. A systematic search was conducted by three independent researchers, who screened articles published up to March/2016, to identify the studies that contained sufficient and clear information on the association of the medicinal plants and periodontitis in murine models. The searches were performed using PubMed, Cochrane, and Science Direct databases. Results. After a critical analysis of titles and abstracts, 30 studies were finally eligible for analysis. The studies presented a great diversity of the experiment designed regarding the methods of induced periodontitis and the evaluation of the medicinal plants efficacy. None of the studies described the possible toxic effects associated with the administration of the plant material to animals and whether they could prevent damage to organs caused by systemic effect of induced periodontitis. Gel-based formulations containing plant substances are seen as an interesting strategy to treat periodontitis. Conclusions. In this systematic review, the state-of-the-art knowledge on the medicinal plants and the induced periodontitis was critically evaluated and discussed from the experiment designed to the possible clinical application.

Ectodermal dysplasia (ED) is a genetically heterogeneous condition resulting from clinical anomalies of structures derived from the ectoderm, such as the hair, nails, sweat glands, and teeth. This clinical report presents the case of a child diagnosed with hypohidrotic ED at 2 years of age; clinical and imaging evaluation was performed with 6-year follow-up, and we present details of the prosthetic dental care, with a 12-month follow-up. The patient's masticatory capacity had improved, leading to the child gaining 4 kg. In conclusion, prosthetic management was noninvasive and appeared to lead to developmental benefits for the patient.

Odontogenic cysts have a high prevalence in the dental clinic population, with dentigerous cyst being one of the most frequent ones and whose aetiology involves accumulation of fluid between the reduced enamel epithelium and the crown of an unerupted tooth. In the diagnostic process of these lesions, one should consider complementary imaging exams such as conventional radiography and computed tomography, which are commonly used for providing anatomical information on the tissues compromised by the lesion, but not on the nature of it. Magnetic resonance imaging (MRI) scans are noninvasive modalities which, due to their unique acquisition characteristics, can provide distinct information on the nature of the lesion. This study reports on a case of dentigerous cyst in the mandible of a 9-year-old patient, documented by means of different imaging modalities. MRI played an important role in both diagnosis of the lesion and differential diagnosis between neoplastic lesions presenting similar imagenological behaviour under other techniques of radiography.

<p align="justify"><span style="color: #000000;"><span style="font-family: Arial, serif;"><span><span lang="en-US">A case of solitary fibrous tumor is reported. Solitary fibrous tumor is a rare neoplasia characterized by the proliferation of fusiform cells of mesenchymal origin accounting for at least </span></span></span></span><span style="font-family: Arial, serif;"><span><span lang="en-US">2% of all soft tissue tumors. In this present case, the initial diagnosis was salivary gland tumor because of the location in the hard palate. </span></span></span><span style="color: #000000;"><span style="font-family: Arial, serif;"><span><span lang="en-US">Histologically, the tumor was composed by conjunctive tissue with proliferation of oval and fusiform cells. The immunohistochemical analysis was positive for CD34 and CD99. The lesion was treated by surgical resection. The clinical, imaging, histological and immunohistochemical data are discussed in this study. </span></span></span></span></p><p lang="en-US" align="justify"> </p><p align="justify"><span style="color: #000000;"><span style="font-family: Arial, serif;"><span><span lang="en-US"><strong><span>Keywords</span></strong></span></span></span></span></p><p align="justify"><span style="font-family: Arial, serif;"><span><span lang="en-US">Solitary fibrous tumor; Oral cavity; Hard palate; Differential diagnosis.</span></span></span></p><p lang="en-US" align="justify"> </p>

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) occurs by the use of a drug that has osteonecrosis as one of its side effects. Case Report: We describe a case of a 48-year-old oncological patient who had brain and bone metastasis due to breast cancer and was medicated with bisphosphonates (BPs). She presented cavities, and after an incorrect exodontia, the lesion evolved into a jaw osteonecrosis. Then she did a sequestrectomy and was treated using laser therapy. Radiological and clinical features are also described. Conclusion:In a case like this, we notice how necessary is a complete evaluation of the oncological patient before some procedures and laser therapy as an effective ally in the management.

Objetivo: Identificar a relação entre a Doença de Kawasaki e o novo Coronavírus (COVID-19). Revisão bibliográfica: Foram analisados 91 artigos, sendo 39 lidos integralmente e utilizados neste estudo. A análise viabilizou a percepção de que infecções pelo novo Coronavírus levam a uma resposta hiperinflamatória ou tempestade de citocinas, como interleucinas (IL) 1 e 6, ativação de macrófagos e presença de imunoglobulina (Ig) A, provocando patologias como linfohistiocitose hemofagocítica secundária, Síndrome de Disfunção Respiratória Aguda (SDRA) e alterações nas artérias coronarianas semelhantes à Doença de Kawasaki. O dano epitelial provocado pelo vírus em estágio inicial, assim como na DK, pode induzir à endotelite local secundária, o que pode explicar um fenótipo vasculítico autoinflamatório tardio com regulação positiva de interleucinas. Essa inflamação endotelial aumentada e lesão/disfunção após a infecção pelo novo Coronavírus, provavelmente, é devido à ação da enzima conversora de angiotensina (ECA). Considerações finais: Nos últimos 20 anos, os vírus da família dos Coronavírus foram propostos como participantes na patogênese da doença de Kawasaki (DK), uma vasculite sistêmica aguda. A associação documentada levanta a preocupação de saber se a infecção por COVID-19 aumenta o risco de DK.

<p><strong>Objective: </strong>The aim of the study was to evaluate the frequency of distal caries in the second molar influenced by the angulation of the third molar adjacent on panoramic radiographs in a clinical dental radiology. <strong>Material and</strong><strong> Methods: </strong>A descriptive and quantitative study that examined 750 panoramic radiographs, of this total, 120 were in accordance with the inclusion criteria of the study was conducted.<strong> Results: </strong>157 seconds and third molars analyzed the prevalence of caries in the distal of the second molar was 25.5%. The most prevalent angle position of the third molar was 57.3% with the vertical, but the position with the highest percentage of decayed molar second distal mesioangular was 50% of the cases. The elements listed, males obtained 40% of second molar distal caries versus 17% for females. People aged 35 or older had the highest incidence with 50% distal caries while other bands obtained 16.21% in the group 18-24 years, and 23.52% in 25-34 years. <strong> Conclusion: </strong>It was possible to establish a sliding scale on the indication for prophylactic removal of mandibular third molar according to the angulation of Winter: horizontal, mesioangular, vertical and distoangular. One can also see a greater relevance to the indication of prophylactic removal of male individuals aged over 35 years.</p>

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