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Around 20% of Brazilian coffee production corresponds to defective beans (PVA), which decreases the quality of the coffee brews. Steam treatment has been reported as an alternative to improve the cup quality of coffee products. This research aimed to study the feasibility of using steamed Robusta PVA beans in instant coffee products. After the steam treatment (2 bar for 3 min), the Robusta PVA was dried, roasted, subjected to extraction in a pilot plant, and freeze-dried. The steamed and untreated Robusta PVA materials (raw, roasted, and instant coffees) and blends of instant Arabica coffee with PVA were characterized. The steamed Robusta PVA instant coffee presented 7.01 g caffeine and 8.74 g total chlorogenic acids in 100 g product. Instant coffee blends with 30% and 50% of steamed Robusta PVA in Arabica coffee were studied. A sensory difference between blends with steamed and untreated Robusta PVA was only perceived by the addition of 50% PVA. The blend with 50% of steamed coffee was preferred and well accepted (average grade of 7.9 on a 10-scale). The use of steamed Robusta PVA coffee (under mild steam treatment conditions, 2 bar/3 min) in instant coffee was viable, and it was obtained an instant coffee to be used in a blend with 50% of Arabica coffee with a good profile of bioactive compounds and sensory acceptance.

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Gynoid lipodystrophy (GL), popularly known as cellulite, affects 85% of women after puberty. The aim of the study was to develop, characterize and evaluate the effectiveness of a topical formulation based on Coffea canephora green extract (GCE) applied by phonophoresis in the treatment of GL in young women. Formulations with 1.0% (w/w) and 3.0% (w/w) of GCE were developed and characterized by organoleptic analysis, pH, centrifugation, caffeine content, rheology, spreadability, preliminary stability and cytotoxic analysis. And after the selection of the formulation, in a longitudinal, randomized and blind study, with volunteers in separate groups, the Control Group (CG, n=15) used the formulation based on a copolymer of sodium acrylates and lecithin (Lec) and the Test Group (TG, n=15) the copolymer formulation of sodium acrylates and lecithin containing 3.0% (w/w) of GCE (Lec/GCE3). Volunteers were assessed before and after treatment for cellulite severity using the Cellulite Severity Scale (CSS) and quality of life using the Dermatology Life Quality Index (DLQI-BRA). The groups were treated with 5 sessions, twice a week, 20 min/session. As a result, the GT achieved a significant reduction (p=0.002) in cellulite severity according to the CSS and both groups showed significant changes in the DLQI-BRA after treatment, CG (p=0.001) and TG (p=0.001). We conclude that the LEC/GCE3 formulation applied by phonophoresis was effective for cellulite in young women.