The aetiopathogenetic mechanism of sudden sensorineural hearing loss (SSNHL) is still unclear. Microvascular impairment is one of the possible reported causes of SSNHL; nonetheless, few studies in the literature have investigated the association between SSHNL and vascular disease and a cause-effect relationship still has to be demonstrated. Two cases of SSNHL are presented and the possible role of vascular disorders in the pathogenesis of this disease is discussed.
Background. Carcinosarcoma is an extremely rare malignant neoplasm, with both a malignant epithelial and mesenchymal component, that rarely affects the larynx. Aim. Aim of this paper is to describe the case of a patient affected by a larynx carcinosarcoma treated by endoscopic horizontal partial laryngectomy with CO(2) laser and particularly discuss the histogenetic hypothesis as well as the possible treatment modalities of this rare lesion. Methods. Case report and literature review. Discussion and Conclusion. Still little is known about the biology of carcinosarcoma and there is still no consensus in the literature on the treatment of these tumors. Endoscopic horizontal partial laryngectomy could represent another treatment option in selected cases.
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