Objective: Surgical correction of the deformity and plaque caused by Peyronie's disease has some important disadvantages and extracorporeal shockwave therapy (ESWT) emerged as a new promising therapy. We evaluated prospectively the efficacy and safety of the association of high dose vitamin E and ESWT as a non-invasive treatment for the disease.Materials and Methods: Twenty-five patients 42 to 68 years old (mean = 54) presenting penile deviation and sexual distress caused by Peyronie's disease were treated in a non-invasive manner. The time of penile deviation ranged from 16 to 52 months (mean = 30). All patients had previous unsuccessful treatment for Peyronie's disease. The angulation's deformity of the penis was assessed by photography at home. The patients received vitamin E (l.200 mg daily) during 3 months and underwent 3 to 6 sessions (mean = 3) of ESWT (3,000 to 4,000 shockwaves) at a power level of l to 2 at 1-week intervals.Results: From 25 patients treated, 16 (64%) reported an improvement in penile angulation, with a mean reduction of 21 degrees (10 to 40). Eight patients reported improvement in their spontaneous erections. Overall, the patients presented only minimal bruising at the site of treatment and skin hematoma. Four patients presented urethral bleeding. The mean angulation after treatment in the control group was 48.67 degrees (30 -70) and in the study group was 24.42 degrees (0 -70), statistically significant.Conclusion: Considering the common complications and the unsatisfactory outcome of the surgical correction for Peyronie's disease, the association of high dose vitamin E and ESWT represents a good option for a non-invasive, effective and safe treatment of the penile deformity.
autor da obra What is Global History? [O que é história global?], lançada em 2016 2 . Em seu capítulo introdutório, Conrad expõe seus objetivos: compreender o aumento da popularidade que a linha da história global adquiriu tanto mundialmente quanto dentro da disciplina de História, assim como apresentar uma perspectiva atual de História em oposição ao modelo historiográfico de história universal do século XX, um modelo profundamente eurocêntrico.Segundo o autor, os primeiros esboços de uma história global surgem após a II Guerra Mundial e o interesse pela mesma ganha fôlego já no final do século XX. As principais razões para isso se devem à tendência em encontrar na globalização o ponto de explicação do presente, assim como o de análise das origens históricas de um processo e da revolução comunicacional, um contexto que impactou os historiadores e a maneira como produzem História. Tal efeito se deu tanto a partir das insuficiências dos instrumentos usados pelos profissionais até
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.