BACKGROUND:The U.S. Food and Drug Administration has to date granted approval or emergency use authorization to three vaccines against severe acute respiratory syndrome coronavirus 2 and coronavirus disease 2019. In clinical trials and real-use observational studies, the Pfizer-BioNTech BNT162b2 messenger RNA coronavirus disease 2019 vaccine, as well as the Moderna mRNA-1273 messenger RNA coronavirus disease 2019 vaccine, have demonstrated high efficacy and few adverse events.
RATIONALE: As pain can exacerbate asthma, we hypothesize that people with back pain and asthma experience exacerbation of asthma during flare of back pain. Men and women equally suffer from back pain. Whether sex and age influence the co-occurrence of asthma and back pain has not been determined. METHODS: A cross sectional data analysis was performed using secondary data of adults (n520,588) treated at Kings County Hospital Center (inpatient, Emergency Department, Ambulatory Surgery) between Oct 2015 and March 2017 with ICD 10 code for back pain (M54.) and/or asthma (J45.). Logistic regression was used to determine likelihood of presentation.
RESULTS:The mean age of the study population was 46 yrs 6 15 while the median age was 47 years. Females made up 12,189 (59%) of the study sample and males 8, 399 (41%). The occurrence of asthma with back pain was 404 (2%); of this, 274 (68%) were females and 130 (32%) were males (P <0.001). Age was not significantly associated with the co-occurrence of asthma and back pain. Males were 36% less likely to present with asthma and back pain when compared to females after adjusting for location of treatment and age (OR 0.64 (95% CI: 0.51 to 0.79), P<0.001. CONCLUSIONS: Females were more likely to present with a cooccurrence of asthma and back pain than males in acute care hospital settings. J ALLERGY CLIN IMMUNOL FEBRUARY 2019 AB224 Abstracts MONDAY
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