Palladium catalyzed coupling reactions have emerged as a versatile, convenient, selective and mild protocol that can usually be adapted in any synthetic scheme for important target molecules with various degrees of structural complexity.
An efficient Hiyama coupling reaction between benzylic halide and aryltrialkoxysilane using Pd nanoparticles has been developed. This procedure accommodates various functional groups to yield a diverse range of diarylmethanes which are ubiquitous units of natural products and pharmaceuticals.
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