The aflatoxin producing fungi Aspergillus flavus, Aspergillus parasiticus, and Aspergillus nomius are highly hepatotoxic, carcinogenic and immunosuppressive which can spread quickly in environment and contaminate stored food. It can lead to serious threats to both human and animal health hazards by causing various diseases. Aflatoxin can breakdown DNA and causes genomic damage during cell division, leading to cancer even death where these breakdown products accumulate in the liver. The chemistry and biosynthesis process of the aflatoxin is discussed in present review study in a nutshell along with their occurrences and the health hazards to human. This review focuses on sources, production, biosynthesis, toxicology, detection, and control techniques of aflatoxins to assure food safety. Present review study is valuable as it provides knowledge on aflatoxins toxicity which helps in food security and safety as well as reduces human diseases in future.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.