The influence of phenolic compounds extracts from three colored rice cultivars on gut microbiota was investigated. The results revealed that protocatechuic acid, chlorogenic acid, caffeic acid and p-coumaric acid were...
Considering
that the study on the impact of the long-term consumption
of resistant starch on metabolic syndromes induced by a high-fat diet
(HFD) is rare, this investigation designed a 36-week consumption of
HFD containing three RS levels (LRS, MRS, and HRS) for measuring changes
in serum parameters, liver transcriptome, and gut microbiota. Results
indicated that all levels of RS in HFD significantly reduced food
intakes and body gain, followed by increased leptin and PYY, but did
not show dose-dependence. Furthermore, MRS triggered a greater number
of enriched pathways than the other RS groups, whereas no enriched
pathway was noted in the HRS group. The Firmicutes/Bacteroidetes ratio can still predict changes in
body weight for long-term observation, and isobutyrate was found to
be positively related to Blautia. Importantly, a
shifted ratio of Ruminococcaceae/Lactobacillaceae quickly occurred in the early stage of 12 weeks for all groups,
but the ratio remained constant in HRS rather than in LRS and MRS,
which might indicate both similarity and difference in the regulation
of the metabolic syndromes among the three RS interventions.
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