Children are more susceptible than adults to acquire central nervous system (CNS) infections. This study assesses the validity of routine cerebrospinal fluid (CSF) culture with the meningitis/encephalitis (ME) FilmArray to detect etiological agents in CNS infections. Based on CSF culture, only 5/40 samples were positive in suspected meningitis, whereas 24/40 samples were positive with the ME FilmArray (p?=?0.01). Sensitivity and specificity of conventional culture method were 55.81 and 100%. Overall disability adjusted life years in the study cohort was 1,603.5. Conventional culture with clinical suspicion alone is not enough to obtain an etiological diagnosis of meningitis. The implementation of novel diagnostic techniques is crucial.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.