During the COVID-19 pandemic, huge interstitial lung disease (ILD) lung images have been captured. It is high time to develop the efficient segmentation techniques utilized to separate the anatomical structures and ILD patterns for disease and infection level identification. The effectiveness of disease classification directly depends on the accuracy of initial stages like preprocessing and segmentation. This paper proposed a hybrid segmentation algorithm designed for ILD images by taking advantage of superpixel and K-means clustering approaches. Segmented superpixel images adapt the better irregular local and spatial neighborhoods that are helpful to improving the performance of K-means clustering-based ILD image segmentation. To overcome the limitations of multiclass belongings, semiadaptive wavelet-based fusion is applied over selected K-means clusters. The performance of the proposed SPFKMC was compared with that of 3-class Fuzzy C-Means clustering (FCM) and K-Means clustering in terms of accuracy, Jaccard similarity index, and Dice similarity coefficient. The SPFKMC algorithm gives an accuracy of 99.28%, DSC 98.72%, and JSI 97.87%. The proposed Fused Clustering gives better results as compared to traditional K-means clustering segmentation with wavelet-based fused cluster results.
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