Mesozoic seafloor spreading anomalies MO-M10 have been identified in the Natal Valley between the south-eastern African margin and the Mozambique Ridge. These identifications confirm that seafloor spreading north and south o f the Falkland Agulhas Fracture Zone (FAFZ) began simultaneously. The Natal Valley anomalies are offset -1300km by the FAFZ from their equivalents in the southern Cape Basin. Their positions confirm that the Tugela Ridge marks the continent/ocean boundary (COB) in the Natal Valley. We have computed successive Falkland Plateau palaeopositions using Natal Valley and Georgia Basin anomalies. These show that the offset in spreading ridges at the FAFZ remained -1300km long from M10 to MO time. By anomaly 34 time, the offset was -1270 km. Therefore no major ridge jumps had occurred by then. Dating MO as 108 Myr BP and anomaly 34 as 80 Myr B P , the average halfspreading rate immediately south of the FAFZ for the Cretaceous Normal Polarity Epoch is 4.2 cm yr-' . Using this, we date: (a) the change in early pole of rotation at 105 Myr; (b) a reconstruction which juxtaposes salt boundaries in the Brazil and Angolan basins at 103.7 Myr; (c) final separation of the Falkland Plateau from southern Africa at 98.3 Myr; (d) the formation of the oceanic northern part of the Agulhas Plateau at 97.3-90.7 Myr.Comparison of magnetic data with implied COB positions in the southernmost Cape and Argentine Basins, and the Georgia Basin suggests continental separation began 122-1 27 Myr BP with undeformed magnetic anomalies dating from 122 Myr (M10). These dates are consistent with micropalaeontological and sedimentological data around southern Africa.

Vertically transmitted HIV infection is a major problem in the developing world due to the poor availability of antiretroviral agents to pregnant women. HIV is a neurotrophic virus and causes devastating neurological insults to the immature brain. The effects of the virus are further compounded by the opportunistic infections and neoplasms that occur as a result of the associated immune suppression. This review focuses on the imaging features of HIV infection and its complications in the central nervous system.

Neurologic tuberculous pseudoabscesses that clinically progress despite conventional antituberculosis therapy may be responsive to adjuvant thalidomide, a potent tumor necrosis factor-α inhibitor. In this study, the addition of thalidomide provided substantial clinical benefit in the majority of patients, and magnetic resonance imaging evolution of lesions from early-stage "T2 bright" with edema to "T2 black" represented a marker of cure.