KyushuDental Society YLJHtldek.;i,:, 34 (6) :615N625, 1981・ t 1-me tw o !h R e}2 ts Eff ve fLVHHpaF{-Jc・12kFFtsill\xeg [1twnc : alesmeasvanv) .JLvHsge$:}]k:\i.I,1esre1suvmth {ttsg : ptiiptlftaxer)/ llZi ft ER llfilllls661i 1 J'1 23 H eeN-7RkS{[ a]) ee R'eg , waliN54t,P{ 6 Jii 9 H za391al YLJH caIiF\,A,,tsftSLtsL i-C vafi U t[. The relationship between the local and the systemic immune response was considered by investigating the process producing each immunoglobuline in the domain of the oral cavity. Namely, the leukocyte, epithelial cell and secretory IgA (SIgA) in human saliva were examined in the healthy adults and the patients with periodontal disease. Using rats immunized with inactive Staphylococcus aureus 209p, the change in the immunoglobulin levels in the serum was examined by the week.
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