Acute leukemia, secondary myelodysplasia and paroxysmal nocturnal hemoglobinuria evolving from severe aplastic anemia (AA) following immunosuppressive therapy are well recognized. However, severe AA occurring after complete remission of acute promyelocytic leukemia (APL) has been documented only once in 2009. We report a case of 30-year-old male diagnosed with APL who achieved complete cytogenetic remission with all-trans retinoic acid based induction regimen and developed severe AA few months later during maintenance therapy.
Introduction: Proper management of diabetic foot infections needs identification and isolation of associated pathogens along with a selection of appropriate antibiotic therapy based on culture and sensitivity. Aims and Objectives: The present study was conducted to assess the prevalence, microbiologic, and clinical profile of subjects having diabetic feet. Materials and Methods: The present retrospective clinical study assessed bacterial culture on tissue samples, pus swabs, and bacterial pus isolates from subjects with diabetic foot admitted to the institute. Results: Enterococcus spp was seen in one subject with Grade 3 disease, streptococcus spp was seen in 1 subject with Grade 3 disease and 2 subjects with Grade 4 disease, and in a total of 3.40% (n=3) subjects, MRSA was seen in 1 subject of Grade 2 disease, 1 in grade 3, and 3 subjects with grade 4 disease, and total of 5.68% (n=5) study subjects and staphylococcus aureus was seen in 2 subjects with grade 1 disease, 2 subjects with grade 3 disease, 4 subjects with grade 4 disease, and 1 subject with grade 5 disease, and in a total of 10.22% (n=9) study subjects.
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