Introduction Medical students are in a very demanding environment and are affected by high degree of stress. High levels of anxiety can affect a student's academic performance and also increase the risk of other health‐related problems. This study aims to evaluate, thanks to the intensity of stress manifestations (4DSQ) together with the sense of coherence (SOC), the prevalence of TMD and oral parafunctions in students enrolled in the University of Medical Sciences. Moreover, it aims to evaluate the relationship between the psychosocial manifestations of stress and sense of coherence in relation to gender. Materials and Methods A total of 324 students of Poznań University of Medical Sciences participated in this study. Students were assessed using a three‐part questionnaire: one was to assess symptoms of TMD, the second part was 4DSQ, and the third was a SOC Questionnaire. Results About one‐third of the students in this study presented symptoms of TMD and perceived more intensively symptoms of distress, anxiety, somatization, and depression. They presented a higher level of somatic symptoms and a lower level of Sense of Coherence than students without TMD symptoms. Conclusion There is a strong negative relationship between the sense of coherence and the level of perceived distress, anxiety, somatization, and depression. Female students attending Medical School showed a higher level of somatization of stress but with a higher capacity to overcome challenges as compared to men.

According to the results of this study with instrumental Arcus Digma ultrasound device measurements of mandibular movements, data were provided on irregularities in TMJ function not detected in participants with or without clinical symptoms of TMD.

Amyotrophic lateral sclerosis (ALS) arises from an interplay of genetic mutations and environmental factors. ssRNA viruses are possible ALS risk factors, but testing their interaction with mutations such as in FUS, which encodes an RNA-binding protein, has been difficult due to the lack of a human disease model. Here, we use isogenic induced pluripotent stem cell (iPSC)-derived spinal neurons (SNs) to investigate the interaction between ssRNA viruses and mutant FUS. We find that rabies virus (RABV) spreads ALS phenotypes, including the formation of stress granules (SGs) with aberrant composition due to increased levels of FUS protein, as well as neurodegeneration and reduced restriction activity by FUS mutations. Consistent with this, iPSC-derived SNs harboring mutant FUS are more sensitive to human immunodeficiency virus (HIV-1) and Zika viruses (ZIKV). We demonstrate that RABV and HIV-1 exacerbate cytoplasmic mislocalization of FUS. Our results demonstrate that viral infections worsen ALS pathology in SNs with genetic risk factors, suggesting a novel role for viruses in modulating patient phenotypes.

sEMG is a suitable tool for prosthodontists because it provides objective results on the stomatognathic system muscles function. Pain and other temporomandibular symptoms detected mostly unilaterally significantly increase muscle tension of the masticatory muscles and diminish muscle motor units recruitment during maximal contraction. Effects may spread to the neck and shoulder girdle muscles.

Our findings suggest that it may be useful for pediatricians and neurologists to include TMD dysfunctions as a part of a standard examination of adolescents presenting with persistent headaches.

SummaryBackgroundDentigenous, infectious foci are frequently associated with the development of various diseases. The role of such foci in the evolution of endocarditis still remains unclear. This article presents the concluding results of an interdisciplinary study verifying the influence of dentigenous, infectious foci on the development of infective endocarditis.Material/MethodsThe study subjects were 60 adult patients with history of infective endocarditis and coexistent acquired heart disease, along with the presence at least 2 odontogenic infectious foci (ie, 2 or more teeth with gangrenous pulp and periodontitis). The group had earlier been qualified for the procedure of heart valve replacement. Swabs of removed heart valve tissue with inflammatory lesions and blood were then examined microbiologically. Swabs of root canals and their periapical areas, of periodontal pockets, and of heart valves were also collected.ResultsMicrobial flora, cultured from intradental foci, blood and heart valves, fully corresponded in 14 patients. This was accompanied in almost all cases by more advanced periodontitis (2nd degree, Scandinavian classification), irrespective of the bacterial co-occurrence mentioned. In the remaining patients, such consistency was not found.ConclusionsAmong various dentigenous, infectious foci, the intradental foci appear to constitute a risk factor for infective endocarditis.

The aim of this study was to assess the occurrence of non-specific symptoms of “long-COVID syndrome” depending on the physical activity undertaken resulting from the imposed forms of study (distance learning–contact learning); 136 men aged 21.5 ± 1.58 from universities educating students of medical faculties were examined. The difference between the universities was mainly due to the nature of the classes undertaken (classes remotely-hybrid form) in the period from March 2020 to February 2021. Among the respondents, 17% in Group I and 16% in Group II were infected with the SARS-CoV-2 virus, including 50% in Group I with moderate symptoms, and in Group II—most people 45% with mild symptoms. The conducted research clearly shows the impact of the COVID-19 pandemic on students. They show a number of important problems, such as reduced physical activity, as well as increased body weight and time spent in front of the monitor. They also make it clear that the health consequences of the pandemic affect both people who were infected with the SARS-CoV-2 virus and those who did not suffer from this infection.

Introduction. During the diagnostic process, the clinical examination of the masticatory system combined with jaw movement measurements can indicate the presence of temporomandibular disorders (TMD) symptoms. Aim. The aim of the present study was to determine the presence of clinical symptoms of TMD in a group of subjects aged 19–27 years and to analyze the measurable parameters obtained from examinations carried out using the Arcus®digma.Material and methods. Eighty four dentate subjects from 19 to 27 years were recruited from students. Objective signs were studied with Helkimo Anamnetic index (Ai) and the subjective symptoms were evaluated with Gsellmann’s Occlusal Index (OI). Functional examination of the masticatory system was performed using Helkimo Clinical Dysfunction index (Di). Pain symptoms were determined in clinical examination using visual analogue scale. Software of Arcus®digma allowed the analysis of Bennett’s angle and movement, the horizontal condylar inclination, retrusion, anterior guidance and Immediate Side Shift.Results. Occasional pain occurred in 39% of students and correlated with increase of OI index, subjects with higher Di displayed higher values of OI. Comparison of Bennett’s angle values for the right and left TMJ showed the significant asymmetry, similarly like the values of Bennett’s movement and retrusion between the left and right TMJ.Conclusions. Bennett’s angle, Bennett’s movement and retrusion were significant parameters in instrumental evaluation of TMD symptoms. The questionnaire and clinical examination supplemented with axiographic recordings revealed the presence of TMD symptoms in students who were not fully aware of TMJ disorders.