Diamond-Blackfan anemia (DBA) is a rare, genetically determined disorder which is manifested with selective deficiency of erythrocyte line in bone marrow. Patients with DBA are diagnosed with a hypocellular bone marrow with a significant absence of erythroid precursors typically in early childhood. They require chronic treatment with corticosteroids and frequent blood transfusions, stem cell transplantation is also possible. For those., who don ' t respond to corticosteroids therapy, survival depends on blood transfusions. The most common complications of transfusional hemochromatosis are hepatic cirrhosis, cardiomiopathy and endocrinopathies such as hypopitiutarism, hypogonadism, hypothyreosis or diabetes mellitus. DBA patients, therefore, require longterm chelation therapy to avoid these complications.
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