Purpose To evaluate the safety of radioembolization (RE) with 90 Yttrium ( 90 Y) resin microspheres depending on coiling or no-coiling of aberrant/high-risk vessels.
Materials and MethodsEarly and late toxicity after 566 RE procedures were analyzed retrospectively in accordance with the National Cancer Institute's Common Terminology Criteria for Adverse Events (CTCAE v3.0). For optimal safety, aberrant vessels were either coil embolized (n = 240/566, coiling group) or a more peripheral position of the catheter tip was chosen to treat right or left liver lobes (n = 326/566, no-coiling group). Results Clinically relevant late toxicities (CGrade 3) were observed in 1 % of our overall cohort. The no-coiling group had significantly less ''any'' (P = 0.0001) or ''clinically relevant'' (P = 0.0003) early toxicity. There was no significant difference (P [ 0.05) in delayed toxicity in the coiling versus the no-coiling group. No RE-induced liver disease was noted after all 566 procedures. Conclusion RE with 90 Y resin microspheres is a safe and effective treatment option. Performing RE without coil embolization of aberrant vessels prior to treatment could be an alternative for experienced centers.
Ethnographers today find themselves experimenting with new approaches to digital ethnography amid pandemic-related restrictions on research. Yet such developments only accelerate a broader trend toward the dissolution of the traditional ethnographic ‘field’ due to new communications technologies and the emergence of a globalized ‘knowledge economy’. Through six contributions from around the world, this forum explores how the emergence of a more diffuse, interconnected ethnographic field is impacting fieldwork’s status as a rite of passage, creating new affective entanglements and shifting power relationships between researchers and participants. Despite the potential for influence and surveillance that new technologies cede to already powerful institutions, the discussions underline how ethnographic interlocutors are auteurs in their own right—and that ethnographers are also often bit characters in other people’s stories.
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