The present study is the first to show increased O2- production in injured vessels and to demonstrate that antioxidant vitamins reduce O2- production. These results suggest that beneficial effects of antioxidant vitamins in coronary artery disease are related, in part, to alterations in vessel redox state.
for the Enhanced Myocardial Efficacy and Recovery by Aspiration of Liberated Debris (EMERALD) Investigators M YOCARDIAL SALVAGE IS frequently suboptimal after percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI), and mortality remains excessive in highrisk subgroups. 1-4 Despite normal epicardial Thrombolysis in Myocardial Infarction (TIMI) flow after primary PCI, myocardial perfusion (as assessed either by angiographic capillary opaci-fication [myocardial blush] or electrocardiographic ST-segment resolution [STR]) is abnormal in a significant proportion of patients, contributing to For editorial comment see p 1116.
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