The historical development of equations used to relate alcohol and real extract to apparent extract and original gravity, as well as ratios between the corrected Real (RDF) and Apparent Degrees of Fermentation (ADF), were examined in light of modern polynomial and non‐linear regression techniques. Comparisons were performed using an extensive data set of 532 brews obtained from commercial and pilot fermentations with statistical error analysis of these empirical relationships. New predictions of apparent extract were calculated as a function of alcohol and real extract analogous to the Improved Tabarie's formula. In addition, attempts at improving Balling's original equation model estimating original gravity from alcohol and real extract are detailed and discussed. The statistical analyses of relationships between Aw/w (alcohol by weight) and functions of OE (Original Extract), AE (Apparent Extract) and RE (Real Extract) as well as ratios between the corrected Real and Apparent Degrees of Fermentation (RDF/ADF) are reported. It is expected that this paper will be useful for brewers to more accurately estimate Aw/w and real extract values.
Fish oil is available primarily as triacylglycerols (TAG) or ethyl esters (EE). Anecdotal evidence suggests that TAG have superior bioavailability and oxidative stability compared to EE. In this work, peroxide value (PV) and p‐anisidine value (AV) were used to monitor oxidation in commercially available TAG and EE fish oils incubated at temperatures from 5 to 60 °C. Pseudo first‐order kinetics were assumed and rate constants were calculated for each temperature. At all temperatures, the rates of oxidation were higher for EE oils than TAG oils. For PV and AV measured in both oils, non‐linear Arrhenius models were plotted, generating activation energies that ranged from 7 to 103 and 2 to 159 kJ/mol for PV and AV, respectively. Although TAG were more resistant to oxidation than EE, they had lower activation energies (Ea) at ≤15 °C for reactions measured with PV and AV. The Ea for EE was negative at temperatures ≥45 °C, indicating that reaction rate was influenced by factors in addition to temperature.
Fish used in the production of fish oil supplements appear to have accumulated petrogenic hydrocarbons in their tissues which were not removed by minimal oil refining. Further study is required to determine if there are any health implications associated with long-term consumption of these contaminated supplements.
Summary
Background/purpose
Sunburn and other health risks associated with excess sun exposure place huge economic burdens on societies, and create discomfort and disease within susceptible individuals. Oral supplements that reduce sunburn may be advantageous. This study evaluated the safety and efficacy of Bend Skincare Anti‐Aging Formula to ameliorate sunburn induced with a solar simulator.
Methods
Subjects (n = 28) with Fitzpatrick skin phototypes I, II, or III took 4 capsules daily of the supplement providing 1400 mg of eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA), 120 mg of gamma‐linolenic acid (GLA), 5 mg of lutein, 2.5 mg of zeaxanthin, and 1000 IU of vitamin D3 for 8 weeks. Skin on each subject's back was exposed to a progressive sequence of timed ultraviolet (UV) radiation exposure doses at baseline, and after 4‐ and 8‐week treatment to determine their minimal erythema dose (MED). Results were compared before and after treatment using 3 paired t tests and subsequently 3 linear mixed models.
Results
Treatment significantly improved tolerance to UV exposure as evidenced by increased MED at 4 and 8 weeks compared with baseline (P < .001). This protection increased with prolonged use of Bend Skincare Anti‐Aging Formula as demonstrated by progressively increased MED between baseline and 4 weeks, and again between 4 and 8 weeks (P < .001). Nearly 86% of patients responded to treatment within 4 weeks and 100% of patients responded by the end of the study, resulting in a 39% mean increase in MED at 4 weeks, and an 84% mean increase in MED at 8 weeks compared with baseline. Treatment was well tolerated with no product associated adverse events (AE) and only a few mild and expected side effects.
Conclusion
Bend Skincare Anti‐Aging Formula safely and effectively provides significant skin photoprotection that increases with continued use.
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