A 20-year-old man with a 9-year history of unusual subcutaneous morphea with nodular lesions in a circular arrangement and wooden-hard symmetrical induration of the arms, had high titers of fibronectin antibodies. A possible role of fibronectin and antifibronectin antibodies in the pathogenesis of scleroderma is discussed.
Bacterial infections of the skin or soft tissue responded to ciprofloxacin 500 mg tablets b.i.d. The treatment was well tolerated and effective, so that this drug can be recommended in cutaneous infections caused by sensitive bacteria.
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