Clothing-comfort assessment by human perception analysis provides a sound basis for comparison of apparel garments under combined microclimates and human-activity levels of normal wear. The perception-analysis process attempts to seek out the wearing conditions that produce differences in human sensation and the descriptors used by indixiduals to describe these sensations.Details of the human perception approach to comfort are illustrated by applications to a shirt and a jeans study involving men and women. The comfort preference for cotton garments in these studies is documented using statistical analysis of the data appropriate to the perception process.