No abstract

In the United States, a small proportion of private donors gives to international charity. We explore the profile of these donors with a view to understanding who supports international causes relative to domestic causes only and, more generally, what shapes public concern for those in need in other countries. Using data from the 2001 survey on “Giving and Volunteering in the United States,” we employ a series of probit regressions to compare the sociodemographic correlates of giving to international causes with 11 other domestic causes such as health, education, and the arts. We find that while income is not associated with the likelihood of international giving, postgraduate education, being foreign-born, and religiosity are large and significant predictors. We also explore the impact of various measures of social capital and civic engagement, and find that institutional trust and youth volunteering are strongly associated with international giving relative to the other causes.

No abstract

Background and Purpose-Vertebral artery hypoplasia (VAH) is supposed to be a risk factor for posterior circulation ischemia (PCI), particularly in the territory of the posterior inferior cerebellar artery (PICA). The aim of our study was to determine whether VAH impedes perfusion in the dependent PICA territory even in the absence of manifest PCI. Methods-VA diameter was retrospectively measured in 934 consecutive patients who underwent whole-brain multimodal computed tomography because of suspected stroke. VAH was defined by a diameter of ≤2 mm and an asymmetry ratio of ≤1:1.7 of both VAs. We performed blinded computed tomography perfusion reading in patients with VAH without PCI (MRI-confirmed) and in control patients (ratio 1:2) with normal VAs. Four different perfusion maps were evaluated for a relative hypoperfusion in the PICA territory. Results-VAH was found in 146 of 934 patients (15.6%). It was more frequent on the right side (66.1%). Of 146 patients, 59without PCI qualified for computed tomography perfusion analysis. Depending on the perfusion map, ≤42.4% (25/59) of patients with VAH, but only 7.6% (9/118) without VAH, showed an ipsilateral PICA hypoperfusion (P<0.001). Sensitivities in patients with VAH were as follows: time to drain 42.4% (25/59)>mean transit time 39.0% (23/59)>cerebral blood flow 25.4% (15/59). Cerebral blood volume was never affected. Conclusions-VAH is a frequent vascular variant that can lead to a relative regional hypoperfusion in the PICA territory.Additional research should clarify the pathophysiological role of VAH in PCI.

Volumetric assessment in WB-CTP is reliable and reproducible. It might serve for a more accurate assessment of stroke outcome prognosis and definition of flow-volume mismatch. Time to drain showed the highest agreement and therefore might be an interesting parameter to define tissue at risk.