Study Objectives Prior work has established associations between post-traumatic stress disorder (PTSD), disrupted sleep, and cardiovascular disease (CVD), but few studies have examined health correlates of nightmares beyond risks conferred by PTSD. This study examined associations between nightmares and CVD in military veterans. Methods Participants were veterans (N=3468; 77% male) serving since September 11, 2001, aged 38 years (SD=10.4); approximately 30% were diagnosed with PTSD. Nightmare frequency and severity was assessed using the Davidson Trauma Scale (DTS). Self-reported medical issues were assessed using the National Vietnam Veterans Readjustment Study Self-report Medical Questionnaire. Mental health disorders were established using the Structured Clinical Interview for DSM-IV. The sample was stratified by the presence or absence of PTSD. Within-group associations between nightmare frequency and severity and self-reported CVD conditions, adjusting for age, sex, race, current smoking, depression, and sleep duration. Results Frequent and severe nightmares during the past week were endorsed by 32% and 35% of participants, respectively. Those endorsing nightmares that were frequent, severe, and the combination thereof were more likely to also evidence high blood pressure (ORs 1.42, OR 1.56, and OR 1.47, respectively) and heart problems (OR 1.43, OR 1.48, and OR 1.59, respectively) after adjusting for PTSD diagnosis and other covariates. Conclusions Nightmare frequency and severity among veterans are associated with cardiovascular conditions, even after controlling for PTSD diagnosis. Study findings suggest that nightmares may be an independent risk factor for CVD. Additional research is needed to validate these findings using confirmed diagnoses and explore potential mechanisms.
Study Objectives The purpose of this study was to (1) estimate trauma associated sleep disorder (TASD) prevalence among post-9/11 era veterans and describe differences in service and comorbid mental health clinical characteristics among individuals with and without probable TASD, and (2) estimate TASD prevalence and characteristics of reported traumatic experiences stratified by sex. Methods We used cross-sectional data from the Post-Deployment Mental Health study of post-9/11 veterans, which enrolled and collected baseline data from 2005 to 2018. We classified veterans as having probable TASD using self-reported measures: traumatic experiences from the Traumatic Life Events Questionnaire (TLEQ) and items from the Pittsburgh Sleep Quality Index with Addendum for PTSD mapped to TASD diagnostic criteria and ascertained mental health diagnoses (posttraumatic stress disorder [PTSD], major depressive disorder [MDD]) via Structured Clinical Interview for DSM-IV. We calculated effect sizes as prevalence ratios (PR) for categorical variables and Hedges’ g for continuous variables. Results Our final sample included 3,618 veterans (22.7% female). TASD prevalence was 12.1% (95% CI: 11.1%-13.2%) and sex-stratified prevalence was similar for female and male veterans. Veterans with TASD had much higher comorbid prevalence of PTSD (PR: 3.72, 95% CI: 3.41-4.06) and MDD (PR: 3.93, 95% CI: 3.48-4.43). Combat was the highest reported most distressing traumatic experience among veterans with TASD (62.6%). When stratifying by sex, female veterans with TASD had a wider variety of traumatic experiences. Conclusions Our results support the need for improved screening and evaluation for TASD in veterans, which is currently not performed in routine clinical practice.
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