Dentistry leaning towards esthetic restorations have made shade matching a crucial step in fabrication of restorations. It is important to ensure the restorations have the accurate shade, this warrants for a successful treatment. This study aims to evaluate the effect on the color of the shade tabs after disinfection. Shade tab guides from two different shade tabs were used and exposed to three different disinfectants. A Spectrophotometer analysis was done to check for the absorbance value after exposure to the disinfectants. The results showed maximum changes occurred after exposure to sodium hypochlorite. The changes observed increased with increase in the exposure time of the shade guides to the disinfectants. Thus, a standard protocol should be followed in clinics regarding disinfection of shade tabs and ensure a change in the shade guides after three to five years span.
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