The COVID-19 pandemic has become one of the biggest threats to the global healthcare system, creating an unprecedented condition worldwide. The necessity of rapid diagnosis calls for alternative methods to predict the condition of the patient, for which disease severity estimation on the basis of Lung Ultrasound (LUS) can be a safe, radiation-free, flexible, and favorable option. In this paper, a frame-based 4-score disease severity prediction architecture is proposed with the integration of deep convolutional and recurrent neural networks to consider both spatial and temporal features of the LUS frames. The proposed convolutional neural network (CNN) architecture implements an autoencoder network and separable convolutional branches fused with a modified DenseNet-201 network to build a vigorous, noise-free classification model. A five-fold cross-validation scheme is performed to affirm the efficacy of the proposed network. In-depth result analysis shows a promising improvement in the classification performance by introducing the Long Short-Term Memory (LSTM) layers after the proposed CNN architecture by an average of , which is approximately more than the traditional DenseNet architecture alone. From an extensive analysis, it is found that the proposed end-to-end scheme is very effective in detecting COVID-19 severity scores from LUS images.

Lung Ultrasound (LUS) images are considered to be effective for detecting Coronavirus Disease (COVID-19) as an alternative to the existing reverse transcription-polymerase chain reaction (RT-PCR)-based detection scheme. However, the recent literature exhibits a shortage of works dealing with LUS image-based COVID-19 detection. In this paper, a spectral mask enhancement (SpecMEn) scheme is introduced along with a histogram equalization pre-processing stage to reduce the noise effect in LUS images prior to utilizing them for feature extraction. In order to detect the COVID-19 cases, we propose to utilize the SpecMEn pre-processed LUS images in the deep learning (DL) models (namely the SpecMEn-DL method), which offers a better representation of some characteristics features in LUS images and results in very satisfactory classification performance. The performance of the proposed SpecMEn-DL technique is appraised by implementing some state-of-the-art DL models and comparing the results with related studies. It is found that the use of the SpecMEn scheme in DL techniques offers an average increase in accuracy and F 1 score of 11% and 11.75% , respectively, at the video-level. Comprehensive analysis and visualization of the intermediate steps manifest a very satisfactory detection performance creating a flexible and safe alternative option for the clinicians to get assistance while obtaining the immediate evaluation of the patients.

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