Arsenic and hexavalent chromium toxicity results from their ability to interact with sulfahydryl groups of proteins and enzymes, and to substitute phosphorus in a variety of biochemical reactions. Alanine aminotransferase (ALT; E.C: 2.6.1.2) and Aspartate amino transferase (AST; EC 2.6.1.1) play a crucial role in transamination reactions and can be used as potential biomarkers to indicate hepatotoxicity and cellular damage. While histopathological studies in liver tissue require more time and expertise, simple and reliable biochemical analysis of ALT and AST can be used for a rapid assessment of tissue and cellular damage within 96 h. The main objective of this study was to determine the acute effects of arsenic and hexavalent chromium on the activity of ALT and AST in the Indian major carp, Labeo rohita for 24 h and 96 h. Significant increase in the activity of ALT (P < 0.01) from controls in arsenic exposed fish indicates serious hepatic damage and distress condition to the fish. However, no such significant changes were observed in chromium-exposed fish suggesting that arsenic is more toxic to the fish. These findings indicate that ALT and AST are candidate biomarkers for arsenic-induced hepatotoxicity in Labeo rohita.
The fully coupled WRF/Chem (Weather Research and Forecasting/Chemistry) model is used to simulate air quality in the Mississippi Gulf coastal region at a high resolution (4 km) for a moderately severe summer ozone episode between 18 CST 7 and 18 CST 10 June 2006. The model sensitivity is studied for meteorological and gaseous criteria pollutants (O3, NO2) using three Planetary Boundary Layer (PBL) and four land surface model (LSM) schemes and comparison of model results with monitoring station observations. Results indicated that a few combinations of PBL and LSMs could reasonably produce realistic meteorological fields and that the combination of Yonsei University (YSU) PBL and NOAH LSM provides best predictions for winds, temperature, humidity and mixed layer depth in the study region for the period of study. The diurnal range in ozone concentration is better estimated by the YSU PBL in association with either 5-layer or NOAH land surface model. The model seems to underestimate the ozone concentrations in the study domain because of underestimation of temperatures and overestimation of winds. The underestimation of NO2by model suggests the necessity of examining the emission data in respect of its accurate representation at model resolution. Quantitative analysis for most monitoring stations indicates that the combination of YSU PBL with NOAH LSM provides the best results for various chemical species with minimum BIAS, RMSE, and high correlation values.
Tropospheric ozone (O3) pollution is a major problem worldwide, including in the United States of America (USA), particularly during the summer months. Ozone oxidative capacity and its impact on human health have attracted the attention of the scientific community. In the USA, sparse spatial observations for O3 may not provide a reliable source of data over a geo-environmental region. Geostatistical Analyst in ArcGIS has the capability to interpolate values in unmonitored geo-spaces of interest. In this study of eastern Texas O3 pollution, hourly episodes for spring and summer 2012 were selectively identified. To visualize the O3 distribution, geostatistical techniques were employed in ArcMap. Using ordinary Kriging, geostatistical layers of O3 for all the studied hours were predicted and mapped at a spatial resolution of 1 kilometer. A decent level of prediction accuracy was achieved and was confirmed from cross-validation results. The mean prediction error was close to 0, the root mean-standardized-prediction error was close to 1, and the root mean square and average standard errors were small. O3 pollution map data can be further used in analysis and modeling studies. Kriging results and O3 decadal trends indicate that the populace in Houston-Sugar Land-Baytown, Dallas-Fort Worth-Arlington, Beaumont-Port Arthur, San Antonio, and Longview are repeatedly exposed to high levels of O3-related pollution, and are prone to the corresponding respiratory and cardiovascular health effects. Optimization of the monitoring network proves to be an added advantage for the accurate prediction of exposure levels.
and frequently observed six chemicals which are carbon monoxide, lead, nitrogen dioxide, ozone, particulate matter, and sulfur dioxide and hazardous pollutants are toxic pollutants which cause cancer and other serious health problems or lead to adverse environmental effects. Anthropogenic primary pollutants such as carbon monoxide, particulate matter, nitrogen oxides and lead are detrimental to health as well as environment. Sulfur dioxide and nitrogen oxides get transformed as sulfuric acid and nitric acid in the atmosphere due to chemical reactions and may fall as acid rain. Some details of these pollutants are briefly described as follows: Carbon monoxide is a colorless, odorless, poisonous gas produced from burning of fuels with carbon and so the major source is road transport vehicles. Due to oxidation process, CO will be transformed as carbon dioxide. The background levels of carbon monoxide are in the range of 10-200 parts per billion (ppb) and urban concentrations generally vary between 10 to 500 parts per million (ppm). Continuous exposure to higher levels (>500 ppm) for longer time periods (> 30 minutes) may lead to headache, dizziness and nausea and also death. Nitric oxide (NO) is a colorless, odorless gas produced during burning of fuel at high temperatures in cars and other road vehicles, heaters and cookers. Mostly, nitrogen dioxide in the atmosphere is formed from the oxidation of nitric oxide (NO). Nitrogen dioxide reacts to form nitric acid and organic nitrates and plays an important role in the production of surface ozone. Mean concentrations in urban areas are in the range of 10-45 ppb reaching as high as 200 ppb. Continuous exposure to NO 2 leads to respiratory problems and lung damage. Particulate matter comprises of both organic and inorganic substances, mainly from dust, fly ash, soot, smoke, aerosols, fumes, mists and condensing vapors and is regarded as coarse particulates with a diameter greater than 2.5 micrometers (µm) and fine particles less than 2.5 micrometers. The acid component of particulate matter (PM) generally occurs as fine particles. Primary sources of the particulate matter are from road transport (25%), noncombustion processes (24%), industrial combustion plants and processes (17%), commercial and residential combustion (16%) and public power generation (15%). In urban areas, secondary particulate matter occurs as sulfates and nitrates with mean values in the range 10-40 µg/m3 and may rise up to higher than 100 µg/m 3. Primary PM sources are derived from both human and natural activities which include agricultural operations, industrial processes, fossil fuel burning etc and secondary pollutants such as SO 2 , NOx, and VOCs are considered as precursors as they help form PM. Measures to reduce these precursor emissions will have a controlling impact on PM concentrations. Fine PM will cause asthma, lung cancer, cardiovascular issues, and premature death and estimated to cause 20,000-50,000 deaths per year in US. Sulfur dioxide (SO 2) is a colorless, nonflammable gas with an...
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