Aim: The aim of this study was to assess the efficacy of glyburide in the treatment of gestational diabetes mellitus and to compare the maternal and fetal outcome between two groups treated either with insulin or glyburide. Material and Methods: Women with gestational diabetes not responding to diet control were randomized into two groups: (i) the control group receiving insulin (n = 32); and (ii) the study group receiving glyburide (n = 32). Primary outcome was assessed in terms of achievement of glycemic control and secondary outcome was assessed by the incidence of maternal and fetal complications in the insulin and glyburide treated groups. Results: The achievement of glycemic control between the insulin and the glyburide treated groups showed no significant difference (97.1%, 93.8%). The occurrence of maternal complications (P = 0.87) and fetal complications (P = 0.32) were comparable between the insulin and glyburide treated groups. Conclusion: Glyburide was found to be as efficacious as insulin in achieving euglycemia in the treatment of gestational diabetic women who require treatment beyond diet control.

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Background: Eclampsia is a hypertensive disorder related to pregnancy, in which there is occurrence of one or more generalized convulsions and or coma, in the absence of other neurologic conditions. It is a common obstetric emergency. It contributes significantly to maternal and perinatal morbidity and mortality. Dr. J. A. Pritchard in 1955, introduced magnesium sulphate for control of convulsions in eclampsia and is used worldwide. Considering the low body mass index of Indian women, a low dose magnesium sulphate regime has been introduced by some authors. The Objective was to compare the efficacy of low dose magnesium sulphate regimen with standard Pritchard"s regimen for eclampsia. Methods: A prospective randomized study of fifty eclampsia cases, treated with magnesium sulphate (25 each with low dose regime and Pritchard regime) was carried out from October 2010 to January 2012 at MAMC & LNH, New Delhi, India. Results were analysed using Statistical Package of Social Sciences (SPSS) software 17.0. Results: In the present study, convulsions were controlled in 96% of eclampsia cases with low dose magnesium sulphate regimen. One case i.e. 4% had single episode of recurrence of convulsion, which was controlled by giving additional drugs and shifted to standard dose regimen. There was no maternal mortality. Conclusions: The maternal and perinatal morbidity and mortality in the present study were comparable to those of standard Pritchard"s regimen. The study did not find a single case of magnesium related toxicity with low dose magnesium sulphate regimen. Low dose magnesium sulphate regimen was found to be safe and effective in eclampsia.

Pregnancy is the most beautiful and memorable time in a woman's life. Apart from medical and obstetrical challenges it involves a of lot emotional, psychological and social aspects too. Although women having medical and obstetrical disorders commonly seek treatment, psychological problems are often not addressed. A female may continue to live in a state of emotional turmoil and may attribute these changes to the hormonal changes in the body due to pregnancy. Psychiatric disorders which remain untreated can disrupt the social life and can have undesirable effects on fetal and neonatal development, so it becomes important to identify women at risk for developing psychiatric disorders during pregnancy and postpartum and initiate timely management. Although the American College of Obstetrics and Gynaecology recommended strongly considering screening pregnant women for depression in 2006, it is not done as a routine.

Background: The aim of the study was to study the awareness, myths and menstrual practices in young girls in a tertiary care center.Methods: Predesigned structured questionnaire based study was done in 180 girls between the age group 13 to17 years, in the outpatient department of a tertiary care hospital in New Delhi. Informed consent was taken before filling up the questionnaire.Results: The participants were ignorant about the importance of proper hygiene and faced a lot restrictions related to daily life during their periods. 68% participants lacked adequate knowledge about the physiology of menstruation. 45% girls were informed regarding menstruation by mothers, sisters and friends whereas teachers played a limited role. 30% girls were using sanitary pads, while most were still using homemade cloths. Pads were being reused in every cycle and they were dried in damp places, preferably during night. Lack of awareness and appropriate care for menstrual morbidities was seen in these girls, which affects their educational attainment. Age old myths and practices still have a lot of impact on the Indian household.Conclusions: Ignorance and myths regarding menstruation still prevail in our society. The need of the hour is starting educational campaigns and schools based initiatives which can educate the girls. Thought should be given in manufacturing low cost sanitary pads as a national program. People especially in the rural set up should be encouraged to improve women’s social and reproductive health situation and counselling should be provided in relation to sanitation and disposal.