Since the beginning of time, man and microbes have coexisted. While certain microbes were capable of living successfully with humans, acting as resident germs that protect and balance the body, harmful bacteria enter and develop in man's tissues, producing infections and physical harm that can occasionally result in death. In the 1940s, antibiotics were discovered and put to use as a result of man's effort for a treatment for her and her numerous bacterial enemies. Antimicrobial are reported to have negative impacts on the beneficial and healthy bacteria of the animal living process while combating disease-causing microorganisms. Antimicrobial use hence depends on the total expected effect while taking into account any adverse side effects. Therefore, it is essential to accurately identify and know the mechanism of action of antimicrobial in order to protect person's health care system. Knowing how medicines fight bacteria has tremendously benefited from modern molecular biology techniques. The classifications of antibiotics are therefore addressed in this work. Key Words: Antimicrobial, Bacteria, Beta-lactums, Macrolides, Tetracyclines
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