Trauma analysis in archaeological human remains can aid our understanding of cultural practices, socio-economic status, environmental and social conditions, and even aspects of a person's occupation. For this reason, fracture patterns and frequencies can be useful in making inferences about the environment people lived and worked in. This is especially true for the 20th century mining industry where unskilled migrant labourers were often subjected to harsh working and living conditions. In this study, the skeletal remains of 36 Chinese indentured mine labourers, who worked and died on the Witwatersrand mines, South Africa, during the period ad 1904-1910, were assessed for evidence of trauma. Historical information suggests that these indentured Chinese labourers were unfamiliar with the workings of deep-level mines and as a result sustained many work-related injuries. Analyses suggest low frequencies of ante-mortem trauma. In the few instances where they occurred, these healed fractures most probably reflect injuries already sustained in China, some time before Chinese indentured employment on the Witwatersrand mines. A high frequency of traumatic lesions, specifically perimortem fractures, however, suggests a drastic shift in their working environment attesting to the hazardous working conditions associated with deep-level mining in the early 20th century.
To address problems of reproducibility related to current age estimation methods, the enhanced computational Methods (ECM) were previously developed using a sample of white North American male pubic symphyses and showed promise in improving current techniques. However, given the evidence of sex and population differences in the onset of age markers, this study set out to test the ECM on a white South African sample. The sample consisted of 184 well‐preserved os coxae from individuals of known age and sex. Pubic symphyseal surfaces were scanned using the Artec Spider 3D scanner, processed using Artec Studio 10 and analyzed using forAge. Point estimates of age were then compared to the true age of each individual. Results indicate that the ECM performed poorly in a white South African population, with consistent underestimation of age‐at‐death and weak positive correlations with true age. Despite the low correlations, the ECM did, however, reduce observer error.
Background
Cytomegalovirus (CMV) infection and disease are preventable complications following pediatric liver transplantation (PLT), despite the use of prophylaxis to minimize the risk of CMV disease. We evaluated the incidence and complications of CMV disease in PLT recipients in South Africa (SA), with particular reference to potential differences in outcome between state and private sector patients.
Methods
Medical records of patients younger than 16 years of age who received liver transplants between January 1, 2012, and August 31, 2018 were analyzed.
Results
Records of all 150 PLT patients were retrieved. The median age at transplant was 29.2 months (95% confidence interval 15.6–58.4) and follow‐up was 46.3 months (interquartile range 27.6–63.1). Sixty‐six (44%) patients were high risk, 79 (52.7%) were intermediate risk, and five (3.3%) were low risk for CMV infection. Forty‐three (28.9%) patients had CMV DNAemia following transplantation, and 30 (20.1%) developed CMV disease. Receipt of care in the private sector was consistently associated with a lower hazard of CMV disease (adjusted hazard ratio [aHR] ranging from 0.36 to 0.43) and a consistently lower hazard of death among recipients at high risk for CMV disease and/or those who developed CMV disease (aHR ranging from 0.28 to 0.33).
Conclusion
Receipt of care in the private health sector was associated with a consistently lower hazard of CMV disease and death in individuals with CMV disease and/or at high risk for CMV disease. Policies aimed at creating a more equitable healthcare system in SA may mitigate the differential burden of illness associated with CMV in PLT recipients.
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