We introduce a novel speckle noise reduction algorithm for OCT images. Contrary to present approaches, the algorithm does not rely on simple averaging of multiple image frames or denoising on the final averaged image. Instead it uses wavelet decompositions of the single frames for a local noise and structure estimation. Based on this analysis, the wavelet detail coefficients are weighted, averaged and reconstructed. At a signal-to-noise gain at about 100% we observe only a minor sharpness decrease, as measured by a full-width-half-maximum reduction of 10.5%. While a similar signal-to-noise gain would require averaging of 29 frames, we achieve this result using only 8 frames as input to the algorithm. A possible application of the proposed algorithm is preprocessing in retinal structure segmentation algorithms, to allow a better differentiation between real tissue information and unwanted speckle noise.
The projection data measured in computed tomography (CT) and, consequently, the slices reconstructed from these data are noisy. We present a new wavelet based structure-preserving method for noise reduction in CT-images that can be used in combination with different reconstruction methods. The approach is based on the assumption that data can be decomposed into information and temporally uncorrelated noise. In CT two spatially identical images can be generated by reconstructions from disjoint subsets of projections: using the latest generation dual source CT-scanners one image can be reconstructed from the projections acquired at the first, the other image from the projections acquired at the second detector. For standard CT-scanners the two images can be generated by splitting up the set of projections into even and odd numbered projections. The resulting images show the same information but differ with respect to image noise. The analysis of correlations between the wavelet representations of the input images allows separating information from noise down to a certain signal-to-noise level. Wavelet coefficients with small correlation are suppressed, while those with high correlations are assumed to represent structures and are preserved. The final noise-suppressed image is reconstructed from the averaged and weighted wavelet coefficients of the input images. The proposed method is robust, of low complexity and adapts itself to the noise in the images. The quantitative and qualitative evaluation based on phantom as well as real clinical data showed, that high noise reduction rates of around 40% can be achieved without noticeable loss of image resolution.
In image-guided interventional procedures, live 2-D X-ray images can be augmented with preoperative 3-D computed tomography or MRI images to provide planning landmarks and enhanced spatial perception. An accurate alignment between the 3-D and 2-D images is a prerequisite for fusion applications. This paper presents a dynamic rigid 2-D/3-D registration framework, which measures the local 3-D-to-2-D misalignment and efficiently constrains the update of both planar and non-planar 3-D rigid transformations using a novel point-to-plane correspondence model. In the simulation evaluation, the proposed method achieved a mean 3-D accuracy of 0.07 mm for the head phantom and 0.05 mm for the thorax phantom using single-view X-ray images. In the evaluation on dynamic motion compensation, our method significantly increases the accuracy comparing with the baseline method. The proposed method is also evaluated on a publicly-available clinical angiogram data set with "gold-standard" registrations. The proposed method achieved a mean 3-D accuracy below 0.8 mm and a mean 2-D accuracy below 0.3 mm using single-view X-ray images. It outperformed the state-of-the-art methods in both accuracy and robustness in single-view registration. The proposed method is intuitive, generic, and suitable for both initial and dynamic registration scenarios.
Registration of pre-operative 3-D volumes to intra-operative 2-D X-ray images is important in minimally invasive medical procedures. Rigid registration can be performed by estimating a global rigid motion that optimizes the alignment of local correspondences. However, inaccurate correspondences challenge the registration performance. To minimize their influence, we estimate optimal weights for correspondences using PointNet. We train the network directly with the criterion to minimize the registration error. We propose an objective function which includes point-to-plane correspondence-based motion estimation and projection error computation, thereby enabling the learning of a weighting strategy that optimally fits the underlying formulation of the registration task in an end-to-end fashion. For single-vertebra registration, we achieve an accuracy of 0.74±0.26 mm and highly improved robustness. The success rate is increased from 79.3 % to 94.3 % and the capture range from 3 mm to 13 mm.
Objective: The signal-to-noise ratio in computed tomography (CT) data should be improved by using adaptive noise estimation for level-dependent threshold determination in the wavelet domain. Method: The projection data measured in CT and, thus, the slices reconstructed from these data are noisy. For a reliable diagnosis and subsequent image processing, like segmentation, the ratio between relevant tissue contrasts and the noise amplitude must be sufficiently large. By separate reconstructions from disjoint subsets of projections, e.g. even and odd numbered projections, two CT volumes can be computed, which only differ with respect to noise. We show that these images allow a position and orientation adaptive noise estimation for level-dependent threshold determination in the wavelet domain. The computed thresholds are applied to the averaged wavelet coefficients of the input data. Results: The final result contains data from the complete set of projections, but shows approximately 50% improvement in signal-to-noise ratio. Conclusions: The proposed noise reduction method adapts itself to the noise power in the images and allows for the reduction of spatially varying and oriented noise.
Abstract-Precise knowledge of the local image noise is an essential ingredient to efficient application of post-processing methods such as wavelet or diffusion filtering to computed tomography (CT) images. The non-stationary, object dependent nature of noise in CT images is a direct result from the noise present in the projection data. Since quantum and electronics noise are the dominating noise sources, comparably simple models can be used for direct noise estimates in the individual projections. In this article, we describe the analytic propagation of these noise estimates through fan-beam filtered backprojection (FBP) reconstruction. Contrary to earlier publications in this field, we include the correlations within the parallel projections resulting from the rebinning, the convolution, and the backprojection processes. The method has been validated against Monte-Carlo results and good accuracy with an average relative error below 3.6% was acchieved for arbitrary objects and over the full range of commonly used convolution kernels and field-of-view settings.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.