Ascorbic acid is one of the major water soluble vitamin and many health benefits have been attributed to ascorbic acid such as antioxidant, anti-atherogenic,immunomodulator anti-carcinogenic etc. It plays a vital role in the biosynthesis of collagen, carnitine and neurotransmitters. As humans can not produce ascorbic acid due to the lack of an enzyme gulonolactone oxidase, it has to be supplemented mainly through fruits, vegetables and tablets. In this present work, we have reported a simple, cost effective, reliable titrimetric method for the estimation of ascorbic acid present in commercially available Vit-C tablets and also the determination of molecular weight of ascorbic acid. The method involves the oxidative dehydrogenation of ascorbic acid by potassium iodate followed by the determination of unreacted potassium iodate by iodometry.
The diverse nature of Chloramine-T, the sodium salt of N-chloro-p-toluenesulfonamide, abbreviated as CAT, acts as a source of halonium cation and nitrogen anion, and acts as both base and nucleophile. It reacts with broad range of functional groups and brings divergent molecular transformations to synthetic chemistry. CAT has also gained much recognition as a mild oxidant for several organic moieties and has been used as a versatile reagent for the estimation of various functional groups in analytical chemistry. This review relays the synthetic and analytic utility of CAT from different literature sources. As aspects of the synthetic utility of CAT have not previously been reviewed, this article gives a comprehensive profile of the CAT reagent for further research development.
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